Results 31 to 40 of about 116,983 (327)

Subcellular Localization of a Glycoprotein Released from Human Platelets upon Stimulation by Thrombin

CHIMIA, 1976
The treatment of washed, intact human blood platelets with 1 U/ml of thrombin for 5 min at 37 °C is linked to the disappearance from the particulate fraction of the homogenized cells of a protein band discernible in the SDS-polyacrylamide gel ...
R. Käser-Glanzmann, M. Jakábová, E.F. Lüscher   +2 more
doaj   +1 more source

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.

Proceedings of the National Academy of Sciences of the United States of America, 1986
A polyclonal antiserum to platelet membrane glycoprotein GPIIb/IIIa was used to detect antigenically related molecules on a diverse panel of human cells.
E. Plow, J. Loftus, E. Levin, D. Fair, D. Dixon, J. Forsyth, M. Ginsberg   +6 more
semanticscholar   +1 more source

Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors. [PDF]

PLoS ONE, 2016
Hsa is a large, serine-rich protein of Streptococcus gordonii DL1 that mediates binding to α2-3-linked sialic acid termini of glycoproteins, including platelet glycoprotein Ibα, and erythrocyte membrane protein glycophorin A, and band 3.
Yumiko Urano-Tashiro, Yukihiro Takahashi, Riyo Oguchi, Kiyoshi Konishi   +3 more
doaj   +1 more source

Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system.

Blood, 1990
The human Baka/Bakb alloantigen system has been implicated in the pathogenesis of post-transfusion purpura and neonatal alloimmune thrombocytopenic purpura.
Suzanne Lyman, R. Aster, G. Visentin, Peter J. Newman   +3 more
semanticscholar   +1 more source

Glanzmann’s thrombasthenia with spontaneous upper gastrointestinal bleeding: a case report

Journal of International Medical Research, 2020
Glanzmann’s thrombasthenia (GT) is a rare bleeding disorder inherited in an autosomal recessive manner. The pathogenesis of GT mainly involves structural abnormalities and dysfunction of platelet membrane glycoprotein IIb/IIIa (integrin αIIbβ3). The most
Zhenguo Qiao, Yi Chen, Wangtianyi Shi, Jun Yang, Yi Song, Jiaqing Shen   +5 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Clinical significance of receptor shedding-platelet GPVI as an emerging diagnostic and therapeutic tool

Platelets, 2017
Platelet membrane bedecked with a wide array of receptors offers a platform to regulate platelet responsiveness, thrombotic propensity, inflammatory disposition, and immune reactivity under diverse pathophysiological conditions.
Madhumita Chatterjee, Meinrad Gawaz
doaj   +1 more source

Targeting macrophage endocytosis via platelet membrane coating for advanced osteoimmunomodulation

iScience, 2022
Summary: The identification, uptake, and clearance of nanoparticles (NPs) by phagocytes are critical in NP-based therapeutics. The cell membrane coating technique has recently emerged as an ideal surface modification approach to help NP bypass ...
Wendong Gao, Lan Xiao, Yuqing Mu, Yin Xiao   +3 more
doaj  

What is the role of Von Willebrand factor in chronic hepatitis B virus infection to hepatocellular carcinoma: a review article

Therapeutic Advances in Chronic Disease, 2022
Von Willebrand factor (VWF) is a glycoprotein synthesized and secreted by vascular endothelial cells and megakaryocytes, found on plasma surface, endothelial cells, and α-granule of platelets.
Qiong Xiang, Jia-Sheng Tao, Jing-Jing Li, Rong-Bo Tian, Xian-Hui Li   +4 more
doaj   +1 more source

Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody.

Journal of Clinical Investigation, 1985
In this study we have used two new monoclonal antibodies, designated LJP5 and LJP9, as well as a previously described one, AP2, all specific for the platelet membrane glycoprotein (GP)IIb/IIIa complex.
V. T. Lombardo, E. Hodson, J. Roberts, T. Kunicki, T. Zimmerman, Z. Ruggeri   +5 more
semanticscholar   +1 more source