Results 41 to 50 of about 122,277 (348)

Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors. [PDF]

PLoS ONE, 2016
Hsa is a large, serine-rich protein of Streptococcus gordonii DL1 that mediates binding to α2-3-linked sialic acid termini of glycoproteins, including platelet glycoprotein Ibα, and erythrocyte membrane protein glycophorin A, and band 3.
Yumiko Urano-Tashiro, Yukihiro Takahashi, Riyo Oguchi, Kiyoshi Konishi   +3 more
doaj   +1 more source

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.

Proceedings of the National Academy of Sciences of the United States of America, 1986
A polyclonal antiserum to platelet membrane glycoprotein GPIIb/IIIa was used to detect antigenically related molecules on a diverse panel of human cells.
E. Plow, J. Loftus, E. Levin, D. Fair, D. Dixon, J. Forsyth, M. Ginsberg   +6 more
semanticscholar   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Clinical significance of receptor shedding-platelet GPVI as an emerging diagnostic and therapeutic tool

Platelets, 2017
Platelet membrane bedecked with a wide array of receptors offers a platform to regulate platelet responsiveness, thrombotic propensity, inflammatory disposition, and immune reactivity under diverse pathophysiological conditions.
Madhumita Chatterjee, Meinrad Gawaz
doaj   +1 more source

What is the role of Von Willebrand factor in chronic hepatitis B virus infection to hepatocellular carcinoma: a review article

Therapeutic Advances in Chronic Disease, 2022
Von Willebrand factor (VWF) is a glycoprotein synthesized and secreted by vascular endothelial cells and megakaryocytes, found on plasma surface, endothelial cells, and α-granule of platelets.
Qiong Xiang, Jia-Sheng Tao, Jing-Jing Li, Rong-Bo Tian, Xian-Hui Li   +4 more
doaj   +1 more source

Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses [PDF]

Biophysical Journal, 96, 2624-2636, (2009), 2008
Enveloped viruses enter host cells either through endocytosis, or by direct fusion of the viral membrane envelope and the membrane of the host cell. However, some viruses, such as HIV-1, HSV-1, and Epstein-Barr can enter a cell through either mechanism, with the choice of pathway often a function of the ambient physical chemical conditions, such as ...
arxiv   +1 more source

Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system.

Blood, 1990
The human Baka/Bakb alloantigen system has been implicated in the pathogenesis of post-transfusion purpura and neonatal alloimmune thrombocytopenic purpura.
Suzanne Lyman, R. Aster, G. Visentin, Peter J. Newman   +3 more
semanticscholar   +1 more source

Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
This review discusses dynamically responsive self‐assembling peptide‐based nano‐drug systems, including the stimulation response, strategy of biomimicry, subcellular internalization, and the applications of peptide nano‐drug materials, and concludes with a brief outlook of their challenges and opportunities in clinical translation.
Yuhan Wang, Jie Zhan, Jinyan Huang, Xing Wang, Zehong Chen, Zhimou Yang, Jie Li   +6 more
wiley   +1 more source

Targeting macrophage endocytosis via platelet membrane coating for advanced osteoimmunomodulation

iScience, 2022
Summary: The identification, uptake, and clearance of nanoparticles (NPs) by phagocytes are critical in NP-based therapeutics. The cell membrane coating technique has recently emerged as an ideal surface modification approach to help NP bypass ...
Wendong Gao, Lan Xiao, Yuqing Mu, Yin Xiao   +3 more
doaj  

Binding of the Streptococcus gordonii surface glycoproteins GspB and Hsa to specific carbohydrate structures on platelet membrane glycoprotein Ibα

Molecular Microbiology, 2005
GspB and Hsa are homologous serine‐rich surface glycoproteins of Streptococcus gordonii strains M99 and Challis, respectively, that mediate the binding of these organisms to platelet membrane glycoprotein (GP) Ibα.
D. Takamatsu, B. Bensing, Hui Cheng, G. Jarvis, I. R. Siboo, José A López, J. Griffiss, P. Sullam   +7 more
semanticscholar   +1 more source