Results 71 to 80 of about 83,070 (313)

The role of cytokines in ovarian cancer drug resistance

International Journal of Cancer, EarlyView.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang, Yunxia Zang, Rebeka Dejenie, Junyuan Bing, Shixia Dong, Yanfei Zhang, Yi Zhu, Jingjing Li   +7 more
wiley   +1 more source

New trend in molecular diagnostics: Insights from the tumor microenvironment

Interdisciplinary Medicine, EarlyView.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan, Jiahui Zhang, Chong Li, Xu Zhang   +3 more
wiley   +1 more source

Cultured human endothelial cells synthesize a plasma membrane protein complex immunologically related to the platelet glycoprotein IIb/IIIa complex [PDF]

, 1986
O. C. Leeksma, J Zandbergen-Spaargaren, JC Giltay, JA van Mourik   +3 more
openalex   +3 more sources

Neonatal Intracranial Hemorrhage with a Dramatic Outcome Due to Maternal Anti CD36 Antibodies

Reports, 2019
Fetal/neonatal allo-immune thrombocytopenia (FNAIT) results from maternal immunization against fetal platelet-specific antigens (HPA) inherited from the father. Most cases involve HPA located on glycoproteins (GP) IbIX, IaIIa and IIbIIIa.
Gérald Bertrand, Virginie Renac, Marie-Christine Lefaix, Carl Nivet, Elise Trudel, Lucie Richard   +5 more
doaj   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, EarlyView.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source

Research progress on modification of hemodialysis membranes with anticoagulant properties [PDF]

Journal of Hebei University of Science and Technology
The dialysis membrane is the most important component of hemodialyzer, and its performance depends on the feasibility and biocompatibility of removing toxic solutes.
Xuan WANG, Zehua LI, Runjie SHI, Tiantian LI, Ruolin WANG, Chunmei NIU   +5 more
doaj   +1 more source

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin, Ming‐Lun Yeh, Po‐Cheng Liang, Shinn‐Cherng Chen, Chung‐Feng Huang, Jee‐Fu Huang, Chia‐Yen Dai, Ming‐Lung Yu, Wan‐Long Chuang   +8 more
wiley   +1 more source

Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting

Journal of Hematology & Oncology, 2019
Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit bioinformation bidirectionally across the plasma membrane.
Jiansong Huang, Xia Li, Xiaofeng Shi, Mark Zhu, Jinghan Wang, Shujuan Huang, Xin Huang, Huafeng Wang, Ling Li, Huan Deng, Yulan Zhou, Jianhua Mao, Zhangbiao Long, Zhixin Ma, Wenle Ye, Jiajia Pan, Xiaodong Xi, Jie Jin   +17 more
doaj   +1 more source

Substrate‐Dependent Variability in Viability and Angiogenic Marker Expression Among Three Endothelial Cell Subtypes: Insights for Artificial Tissue Vascularization

Macromolecular Bioscience, EarlyView.
The study investigates how four ECM‐mimicking biomaterials—fibrin, fibronectin, and non‐crosslinked or crosslinked gelatin—affect different types of human endothelial cells. Cell viability, morphology, and angiogenic marker expression are evaluated. Results reveal substrate‐dependent effects on cell behavior and emphasize the importance of selecting ...
Jernej Vajda, Boštjan Vihar, Marko Milojević, Dragana Bjelić, Amadeja Brečko, Uroš Maver   +5 more
wiley   +1 more source

New trends in the study of podoplanin as a cell morphological regulator

Japanese Dental Science Review, 2010
Podoplanin is a mucin-type glycoprotein firstly identified in podocytes, which is homologous to the type I alveolar cell specific T1α-2 antigen and to the oncofetal antigen M2A recognized by the D2-40 antibody. Podoplanin possesses a platelet aggregation-
Yoshihiko Sawa
doaj   +1 more source