Results 81 to 90 of about 83,070 (313)
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source
Nuts and legumes contain both nutrients and bioactive compounds supporting cardiovascular health related to influencing DNA methylation. These foods are related to reducing oxidative stress, supplying methyl donors, and modulating genes involved in platelet function, such as PEAR1 and mitochondrial genes, in association with helping reduce inflammation
Siwaphorn Chaimati +2 more
wiley +1 more source
Platelet receptors and signaling in the dynamics of thrombus formation
Hemostasis and pathological thrombus formation are dynamic processes that require a co-ordinated series of events involving platelet membrane receptors, bidirectional intracellular signals, and release of platelet proteins and inflammatory substances ...
José Rivera +3 more
doaj +1 more source
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq +6 more
wiley +1 more source
alpha-Actinin and membrane glycoprotein IIIa are different proteins in human blood platelets. [PDF]
Barbara G. Langer +5 more
openalex +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Tissue engineering for tendon and ligament repair: Insights and advances
Tendon and ligament injuries are widespread diseases, leading to severe pain and a consequent reduced mobility. This phenomenon is mainly due to the limited ability to self‐healing of these tissues. Unfortunately, the currently available surgical and rehabilitative treatments suffer frequent complications and incomplete success.
Francesca Romano +3 more
wiley +1 more source
The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis [PDF]
TJ Kunicki +3 more
openalex +1 more source
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng +13 more
wiley +1 more source
BackgroundFlow cytometric platelet activation has emerged as an alternative diagnostic test for inherited platelet disorders. It is, however, labor intensive and few studies have directly compared the performance of flow cytometric platelet activation ...
Kristoffer Navred +6 more
doaj +1 more source

