Results 151 to 160 of about 102,308 (347)
Liposome‐Based Interventions in Knee Osteoarthritis
Small, EarlyView.Liposomes offer new opportunities for the management of knee osteoarthritis (OA). This review examines the last decade's advances, focusing on intra‐articularly (IA) administered liposomes and liposome‐based systems as pharmaceutical carriers and lubricants, while discussing their in vivo efficacy. Functionalized liposomes (with polymers, peptides etc.)
Evgenia Mitsou, Jacob Klein
wiley +1 more source
A Simulation of Blood Cells in Branching Capillaries [PDF]
arXiv, 2008 The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red blood cells, which are the dominant component in blood, the membrane has strong resistance to surface dilatation ...
arxiv
Recent progress on nanotechnologies for enhancing blood‐brain barrier permeability
Smart Molecules, EarlyView.In this review, we summarize innovative strategies for harnessing the power of nanotechnology to enhance blood‐brain barrier permeability, a key challenge for central nervous system (CNS) drug delivery. We overview structural innovation of nanocarriers, improvements in targeting strategies, and nanotechnology‐enhanced brain imaging.
Qibin Liu +4 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2013 Background Antiplatelet aggregation treatment has become a regular treatment of ischemic stroke. The affirmation of antiplatelet therapy is mainly derived from patients with clinical use, which can not provide the laboratory indexes for evaluation of a ...
Zhen ZHAO +5 more
doaj
Human vascular endothelial cells express a membrane protein complex immunochemically indistinguishable from the platelet VLA-2 (glycoprotein Ia-IIa) complex [PDF]
, 1989 JC Giltay +4 more
openalex +1 more source
Neural Operator Modeling of Platelet Geometry and Stress in Shear Flow [PDF]
arXivThrombosis involves processes spanning large-scale fluid flow to sub-cellular events such as platelet activation. Traditional CFD approaches often treat blood as a continuum, which can limit their ability to capture these microscale phenomena. In this paper, we introduce a neural operator-based surrogate model to bridge this gap.
arxiv
Small Science, EarlyView.Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu +12 more
wiley +1 more source
Platelet membrane topography: colocalization of thrombospondin and fibrinogen with the glycoprotein IIb-IIIa complex [PDF]
, 1985 AS Asch, LL Leung, MJ Polley, RL Nachman
openalex +1 more source
Small Structures, EarlyView.Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han +11 more
wiley +1 more source
Thrombin-induced increase in surface expression of epitopes on platelet membrane glycoprotein IIb/IIIa complex and GMP-140 is a function of platelet age [PDF]
, 1989 Brian Savage +4 more
openalex +1 more source