Results 131 to 140 of about 1,304,823 (301)
Artificial Organs, EarlyView.Quantitative assessment of a newly proposed CFD‐based biophysical model for predicting device‐induced platelet damage by circulatory assist devices was performed. The new model preserved the relative trends observed previously with the power‐law formulation across a range of clinically relevant pump operating conditions, while demonstrating improved ...
Anik Tarafder +3 more
wiley +1 more source
Solubilization of lipids and membrane proteins into nanodiscs: Mode of action and applications of SMA copolymers [PDF]
, 2016 Cell membranes separate the inside and outside of cells. Membrane proteins in the cell membrane control the traffic of molecules across the membrane and are therefore targets for a lot of drugs: about 50 % of all approved drugs target a membrane protein!
Scheidelaar, S. +2 more
core
Haematologica, 2000 BACKGROUND AND OBJECTIVE: The effect of local and circulating thrombin on platelet adhesion onto vascular surfaces was explored in the absence of plasma adhesive proteins using flow conditions.
M Diaz-Ricart +6 more
doaj
Review Article: Fibrosis‐4 Index in Steatotic Liver Disease—Past, Present and Future
Alimentary Pharmacology &Therapeutics, EarlyView.FIB‐4 remains an inexpensive, scalable first‐line triage tool for excluding advanced fibrosis and identifying patients who need second‐line assessment, but it should not be used as a stand‐alone diagnostic or treatment‐selection test. Sequential testing and longitudinal FIB‐4 trajectories may improve risk stratification and prognosis.
Kriti Soni +6 more
wiley +1 more source
Role of platelet function and platelet membrane glycoproteins in children with primary immune thrombocytopenia. [PDF]
Mol Med Rep, 2016 Liu WJ +5 more
europepmc +1 more source
Brain Pathology, EarlyView.How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova +11 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
CD93—An emerging vascular target in cancer therapy
British Journal of Pharmacology, EarlyView.Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira +3 more
wiley +1 more source
An investigation into the effects of dystrophin on the lateral mobility of muscle membrane components. [PDF]
, 1999 Dystrophin is the product of the Duchenne Muscular Dystrophy gene locus, whose absence results in progressive skeletal muscle breakdown. Despite considerable work on the localisation of dystrophin and its associated complex, its role in muscle function ...
Dutton, A.L., Dutton, Anna Louise
core
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010 La púrpura trombocitopénica inmunológica es una enfermedad autoinmune, benigna, de aparición frecuente, caracterizada por la presencia de anticuerpos dirigidos contra las glicoproteínas de la membrana plaquetaria que producen una disminución del recuento
Dunia de la C. Castillo-González +3 more
doaj