Results 111 to 120 of about 20,129 (301)

Additional GPI-anchored glycoproteins on human platelets that are absent or deficient in paroxysmal nocturnal haemoglobinuria

, 1993
In order to detect novel glycophosphatidylinositol (GPI)-anchored platelet proteins, human platelets were incubated with PI-specific phospholipase C (PI-PLC) and the supernatant was analysed by PAGE and silver-staining for additional protein bands.
Kenneth J. Clemetson, János Polgár, Daniela Gengenbacher, Polgár, János, Jeannine M. Clemetson, Clemetson, Kenneth J., Clemetson, Jeannine M., Gengenbacher, Daniela   +7 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

A biochemical study on the level of lipids and glycoproteins in the serum and platelets of liver cirrhotic bleeders

, 2006
Bleeding complication and abnormal platelet functions are associated with liver cirrhosis. The aim of the present investigation was to assess the functional integrity of platelets in terms of lipids like cholesterol and phospholipids, glycoproteins and ...
Geetha, Arumugam, Jeyachristy, Sam, Vijayalakshmi, Sivagurunathan   +2 more
core  

Presence of cytoadhesins (IIb-IIIa-like glycoproteins) on human metastatic melanomas but not on benign melanocytes

, 1989
Glycoproteins IIb and IIIa, a heterodimer complex, play a vital role in blood platelet aggregation and are members of a wide family of membrane receptors known as integrins or cytoadhesins.
McGregor, J. L., McGregor, B. C., Hu, C. H., Warnke, R. A., Boukerche, H., Wood, G. S., Weiss, L. M.   +6 more
core   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Evaluation of therapeutic efficacy on combined use of clopidogrel and ozagrel sodium in the treatment of acute ischemic stroke

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Background Antiplatelet aggregation treatment has become a regular treatment of ischemic stroke. The affirmation of antiplatelet therapy is mainly derived from patients with clinical use, which can not provide the laboratory indexes for evaluation of a ...
Zhen ZHAO, Zheng-jun BAO, Xiao-peng LUO, Zi-juan PENG, Xiao-ling CAO, Lan-ying TANG   +5 more
doaj  

Cytomegalovirus host receptor expression in the human fetal inner ear.

PLoS ONE
Fetal infection with human cytomegalovirus (hCMV) can cause sensorineural hearing loss and vestibular impairment, yet its pathogenesis remains unclear. This study aims to identify potential target cell types of hCMV in the human fetal inner ear.
Lucia C M Grijpink, Wouter H van der Valk, Edward S A van Beelen, John C M J de Groot, Heiko Locher, Ann C T M Vossen   +5 more
doaj   +1 more source

Biogenesis of the platelet receptor for fibrinogen: evidence for separate precursors for glycoproteins IIb and IIIa.

, 1986
Congenital absence of platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa) results in a severe bleeding disorder characterized by defective platelet aggregation and failure of fibrinogen to bind to platelets.
McEver, Rodger P, Lingappa, Vishwanath R, Bray, Paul F, Kan, Yuet W, Rosa, Jean-Philippe, Shuman, Marc A   +5 more
core  

Purification of the Porcine Platelet GP IIb-IIIa Complex and the Propolypeptide of von Willebrand Factor

, 1998
SummaryPlatelet membrane glycoproteins (GP) are involved in platelet adhesion and aggregation. The glycoprotein IIb-IIIa complex (GP IIbIIIa) is a Ca2+-dependent heterodimer that binds fibrinogen and other adhesive proteins, thereby mediating platelet ...
Teresa Royo, Royo, Teresita, Lina Badimon, Matilde Vidal, Vidal, Matilde, Badimón Maestro, Lina   +5 more
core   +1 more source

Nano‐Silver‐Selenium Liquid Dressing Facilitates Treatment of Monkeypox and Prevention of Viral Transmission in a Surrogate Mouse Model

Exploration, EarlyView.
There is no effective method to treat this virus and prevent its transmission. To address this, we have developed a nano‐silver‐selenium liquid dressing (AgSe@LD) by combining silver and selenium nanoparticles with commercial liquid dressings. This unique AgSe@LD formulation exhibits good adhesion, stability and toughness and demonstrates efficient ...
Wei Wang, Mengjun Li, Zining Liu, Jiayin Chen, Ke Liu, Fengfang Wei, Junrui Li, Yixuan Xie, Yushan Jiang, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Minghui Yang, Hua Ma, Ruilin Zhang, Chenguang Shen, Yuhui Liao   +15 more
wiley   +1 more source