Results 91 to 100 of about 40,413 (292)

Extracellular Matrix Molecules Facilitating Vascular Biointegration [PDF]

, 2014
All vascular implants, including stents, heart valves and graft materials exhibit suboptimal biocompatibility that significantly reduces their clinical efficacy.
Michael, Praveesuda, Ng, Martin K.C., Waterhouse, Anna, Wise, Steven G.   +3 more
core   +1 more source

A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger, Nicolas Hebert, Laura Bencheikh, Vincent Malcor Deydier de Pierrefeu, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Sandia Adypagavane, Meghan Perkins, Laura Matabishi‐Bibi, France Pirenne, Claire Berquet, Stephane Moutereau, Serge Pissard, Frédéric Galactéros, Michael C. Marden, Pablo Bartolucci   +14 more
wiley   +1 more source

CLONING OF THE 1.4-kb mRNA SPECIES OF HUMAN COMPLEMENT FACTOR H REVEALS A NOVEL MEMBER OF THE SHORT CONSENSUS REPEAT FAMILY RELATED TO THE CARBOXY TERMINAL OF THE CLASSICAL 150-kDa MOLECULE [PDF]

, 1991
Three factor H mRNA species of 4.3 kb, 1.8 kb, and 1.4 kb are constitutively expressed in human liver. Having previously characterized full-length cDNA clones derived from the 4.3-kb and 1.8-kb factor mRNA, we report here the isolation and eucaryotic ...
Dierich, Manfred P., Estaller, C., Koistinen, V., Schwaeble, W., Weiss, Elisabeth H.   +4 more
core   +2 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Efeito protetor de antagonista das gliproteínas IIb/IIa nas alterações hepáticas e pulmonares secundárias à isquemia e reperfusão do fígado em ratos Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat’s liver

Arquivos de Gastroenterologia, 2007
RACIONAL: A lesão de isquemia e reperfusão hepática é um evento comum e responsável por considerável morbidade e mortalidade. OBJETIVO: Avaliar efeitos de inibidor da glicoproteína IIb/IIIa, cloridrato de tirofiban, nas alterações hepáticas e pulmonares ...
Leonardo F. Canedo, Marcel Autran C. Machado, Ana M. M. Coelho, Sandra N. Sampietre, Telesforo Bachella, Marcel C. C. Machado   +5 more
doaj   +1 more source

Adhesion of a chicken myeloblast cell line to fibrinogen and vitronectin through a beta 1-class integrin. [PDF]

, 1992
The adhesive interactions of circulating blood cells are tightly regulated, receptor-mediated events. To establish a model for studies on regulation of cell adhesion, we have examined the adhesive properties of the HD11 chick myeloblast cell line ...
Neugebauer, KM, Reichardt, LF, Venstrom, KA   +2 more
core   +1 more source

Glanzmann thrombasthenia [PDF]

, 2006
Glanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding syndrome affecting the megakaryocyte lineage and characterized by lack of platelet aggregation.
Alan T Nurden
core   +2 more sources

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

Advanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus, Broder Poschkamp, Lea Miebach, Anke Schmidt, Linus Hübner, Julia van der Linde   +5 more
wiley   +1 more source

Impact of sequence variation in the ul128 locus on production of human cytomegalovirus in fibroblast and epithelial cells [PDF]

, 2013
The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A.
A. J. Davison, Adler, Adler, Akter, Baldanti, Borst, Boyle, Britt, Bronzini, Brunak, Cha, Chan, Chowdary, Compton, Compton, Cunningham, D. J. Dargan, Dargan, Davison, Desmet, Dogan, Dolan, Erice, Feire, Fouts, G. S. Wilkie, Genini, Gerna, Gerna, Grazia Revello, Hahn, Hahn, Haspot, I. Murrell, Irmiere, Isaacson, Isaacson, Jiang, Kari, Kelley, Kinzler, Lilleri, Lopper, Macagno, Magri, Matrosovich, Mocarski, Murphy, O'Connor, P. Tomasec, Paredes, Paterson, Prichard, R. J. Stanton, Rasmussen, Reese, Revello, Ryckman, Ryckman, Ryckman, Saccoccio, Schleiss, Schuessler, Schuessler, Schuessler, Scrivano, Sinclair, Sinzger, Sinzger, Sinzger, Sinzger, Smith, Soroceanu, Stanton, Stanton, Stanton, Stanton, Straschewski, Sun, Talbot, Vanarsdall, Vanarsdall, Wang, Wang, Wang, Warming, Wille, Yu   +87 more
core   +2 more sources

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source