Results 71 to 80 of about 20,129 (301)

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

Two novel variants of uncertain significance in GP9 associated with Bernard–Soulier syndrome: Are they true mutations?

open access: yesPlatelets, 2018
Bernard–Soulier syndrome (BSS) is an autosomal recessive major thrombocytopathy, the symptoms of which are mainly marked by mucocutaneous bleeding.
P. Boisseau   +12 more
doaj   +1 more source

Effects of tonsillectomy under general anaesthesia on articulatory characteristics and blood levels of PCT, GMP-140, and T lymphocyte subsets in children with obstructive sleep apnea-hypopnea syndrome [PDF]

open access: yes精准医学杂志
Objective To explore the effects of tonsillectomy under general anesthesia on articulatory characteristics and blood levels of procalcitonin (PCT), platelet membrane protein-140 (GMP-140), and T lymphocyte subsets in children with obstructive sleep apnea-
WANG Zihan, PAN Hongshuai
doaj   +1 more source

Identification of 22 novel mutations in patients with Glanzmann's thrombasthenia

open access: yes, 2008
Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited platelet function defect that characterized by reduction in, or absence of, platelet aggregation in response to multiple physiologic agonists. GT is characterized by normal platelet
Renu Saxena   +6 more
core  

Flow cytometric characterization of platelet activation in platelet concentrates

open access: yes, 2015
A caracterização da expressão das glicoproteínas de superfície plaquetária e superfície pró-coagulante por citometria de fluxo é uma técnica sensível para identificação da ativação plaquetária em concentrados de plaquetas.
Marques Júnior, José F. C.   +1 more
core   +1 more source

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

open access: yesAdvanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus   +5 more
wiley   +1 more source

Complex Formation of Platelet Membrane Glycoproteins

open access: yes, 2014
of purified platelet membrane glycoproteins lIb and IIIa and the generation of monospecific antisera to these membrane proteins. Using these monospecific antisera in an enzyme-linked immunosorbent assay system, it is now demonstrated that glycoprotein ...
Lawrence L. K   +2 more
core  

Inherited disorders of platelets membrane glycoprotein disorders

open access: yes, 2013
İstanbul Bilim Üniversitesi, Tıp Fakültesi.Platelet membrane glycoproteins play a key role in hemostasis and thrombosis. Although disorders of platelet membrane glycoproteins are rare, their effects on the lives of those affected are very important ...
Diz-Küçükkaya, Reyhan, Lopez, Jose A.
core   +1 more source

Biomimetic Nanoparticle Delivering Colchicine to Target Endothelial Inflammation for Atherosclerosis Treatment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Platelet membrane‐coated layered double hydroxide nanoparticles were engineered to target inflamed endothelium at early‐stage atherosclerosis and enhance therapeutic efficacy. The biomimetic platform improves stability, immune escape, and inflamed vascular cell targeting, resulting in reduced oxidative stress and downregulated adhesion molecules.
Xiuwen Zhang   +4 more
wiley   +1 more source

Platelet Membrane-Coated Nanoparticles Target Sclerotic Aortic Valves in ApoE−/− Mice by Multiple Binding Mechanisms Under Pathological Shear Stress

open access: yesInternational Journal of Nanomedicine, 2020
Hongbo Yang, 1,* Yanan Song, 1,* Jing Chen, 1,* Zhiqing Pang, 2 Ning Zhang, 1 Jiatian Cao, 1 Qiaozi Wang, 1 Qiyu Li, 1 Feng Zhang, 1 Yuxiang Dai, 1 Chenguang Li, 1 Zheyong Huang, 1 Juying Qian, 1 Junbo Ge 1 1Department of Cardiology, Zhongshan Hospital,
Yang H   +13 more
doaj  

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