Results 151 to 160 of about 20,129 (301)
The FEBS Journal, EarlyView.The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
The platelet membrane glycoprotein IIb-IIIa complex [PDF]
Blood, 1988 D R, Phillips +3 more
openaire +3 more sources
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley +1 more source
Nature-Inspired Alternatives to PEG for Next-Generation Long-Circulating Nanocarriers. [PDF]
Int J NanomedicineJan N, Rejili M.
europepmc +1 more source
Polymorphisms of platelet glycoproteins in blood donors from Amazonas
, 2015 Humans platelets Antigens (HPA) are specific alloantigens of platelets resulting from single nucleotide polymorphism (SNP) that lead to substitution of an amino acid protein level defined by polymorphisms of platelet surface glycoproteins.
Portela, Cíntia Nicácio
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Journal of Anatomy, EarlyView.p‐STAT3‐positive cells in metabolically relevant peripheral organs and tissues from mice administered with recombinant CNTF (0.3 mg/kg). Abstract Administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight in both humans and experimental animals, where it also ameliorates hyperglycemia, hyperinsulinemia, and dyslipidemia ...
Chiara Galli +6 more
wiley +1 more source
Prevalence and Specificity of Anti-HPA and Anti-HLA Antibodies in Patients with Suspected Immune-Mediated Platelet Disorders: A Single-Center Study from Serbia. [PDF]
Medicina (Kaunas)Vojvodić S, Grujić J.
europepmc +1 more source
, 1988 We have investigated the composition and function of membrane microparticles released from platelets exposed to the C5b-9 proteins of the complement system. Gel-filtered human platelets were incubated with sub-lytic amounts of the purified C5b-9 proteins
T. Weidmer +3 more
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