Results 11 to 20 of about 29,930 (290)
Bio‐inspired functional coacervates
Aggregate, Volume 3, Issue 6, December 2022., 2022 Bio‐inspired functional coacervates have diverse functions. Natural and synthetic coacervates are a new class of materials that have great potential for various biomedical applications, including medical adhesives, drug delivery, and tissue engineering.
Shujun Chen, Qi Guo, Jing Yu
wiley +1 more source
Antibody binding reports spatial heterogeneities in cell membrane organization [PDF]
, 2022 The spatial organization of cell membrane glycoproteins and glycolipids is critical for mediating the binding of ligands, receptors, and macromolecules on the plasma membrane. However, we currently do not have the methods to quantify the spatial heterogeneities of macromolecular crowding on live cell surfaces.
arxiv +1 more source
Platelet membrane glycoproteins: historical perspectives [PDF]
Journal of Thrombosis and Haemostasis, 2006 3–9. The function of blood platelets to prevent blood loss at injured sites in the vasculature depends largely on their capacity to adhere, aggregate, promote coagulation and secrete factors that induce vasoconstriction and recruit inflammatory cells. Produced in large numbers from megakaryocytes, platelets enter the circulation for 7–10 days primed to
D. R. Phillips +2 more
openaire +3 more sources
Molecular and cellular paradigms of multidrug resistance in cancer
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya +6 more
wiley +1 more source
Pathogenic mechanisms contributing to thrombocytopenia in patients with systemic lupus erythematosus
Platelets, 2022 Systemic lupus erythematosus (SLE) is an autoimmune condition developing thrombocytopenia in about 10–15% of cases, however, mechanisms leading to low platelet count were not deeply investigated in this illness.
M. Constanza Baroni Pietto +13 more
doaj +1 more source
Frequency of human platelet antigens −1 to −5 and −15 in Turkmen blood donors
Advanced Biomedical Research, 2023 Background: Due to the presence of platelet antigen polymorphisms, human platelet membrane glycoproteins can be identified as an alloantigen or autoantigen.
Maedeh Nozarimirarkolaei +5 more
doaj +1 more source
von Willebrand Factor unfolding mediates platelet deposition in a model of high-shear thrombosis [PDF]
, 2022 Thrombosis under high-shear conditions is mediated by the mechanosensitive blood glycoprotein von Willebrand Factor (vWF). vWF unfolds in response to strong flow gradients and facilitates rapid recruitment of platelets in flowing blood. While the thrombogenic effect of vWF is well recognized, its conformational response in complex flows has largely ...
arxiv +1 more source
Cytometry Part A, Volume 101, Issue 12, Page 1049-1056, December 2022., 2022 Abstract Extracellular vesicles (EVs) are an upcoming biomarker for disease. However, the measured concentrations of EVs by flow cytometry are incomparable due to analytical variables. This study aimed to investigate how the choice of fluorophore, and thereby brightness, affects the measured concentration of EVs.
Angela Adriana Francisca Gankema +3 more
wiley +1 more source
The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]
, 2005 Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O. +4 more
core +2 more sources
European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023 B lineage cells have been identified as therapeutic targets in autoimmune diseases. In the current review article, we provide an overview of novel strategies to target B lineage cells in autoimmune diseases, with a focus on inflammatory rheumatic diseases.
Ana Merino‐Vico +3 more
wiley +1 more source