Results 271 to 280 of about 102,308 (347)

Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice. [PDF]

Blood Adv
Smith CW, Campos J, Brown HC, Jooss NJ, Ivanova VS, Harbi M, Garcia-Quintanilla L, Jossi S, Perez-Toledo M, Rookes K, Brill A, Theodore LN, Owens T, LaStant J, Foulke MC, Mukai S, Francesco M, Storek M, Hicks A, Langrish C, Nunn PA, Cunningham AF, Chauhan A, Thomas MR, Watson SP, Nicolson PLR.   +25 more
europepmc   +1 more source

The Link Between Venous and Arterial Thrombosis: Is There a Role for Endothelial Dysfunction? [PDF]

Cells
Donadini MP, Calcaterra F, Romualdi E, Ciceri R, Cancellara A, Lodigiani C, Bacci M, Della Bella S, Ageno W, Mavilio D.   +9 more
europepmc   +1 more source

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Platelet Membrane Glycoproteins

, 2017
Platelets are small anucleate blood cells that are produced in the bone marrow from the cytoplasm of megakaryocytes. Circulating platelets are essential for primary hemostasis and also involved in pathological thrombosis. For the platelet hemostatic functions, platelet surface membrane glycoproteins are crucial to form platelet-subendothelial matrix ...
H. Kato, Y. Tomiyama
semanticscholar   +3 more sources

Platelet membrane glycoproteins: functions in cellular interactions.

Annual Review of Cell Biology, 1990
The understanding of the structure and function of platelet membrane glycoproteins has been facilitated by studies showing that they belong to larger gene families of cell surface receptors involved in cellular interactions. In some instances (e.g.
N. Kieffer, D. Phillips
semanticscholar   +4 more sources

Platelet membrane glycoproteins and their function: An overview

Blut, 1989
The membrane glycoproteins (GP) of human platelets act as receptors that mediate two important functions, adhesion to the subendothelial matrix and platelet-platelet cohesion, or aggregation. Many of these glycoprotein receptors exist as noncovalently linked heterodimers, including those that belong to the supergene family of adhesion receptors called ...
T. Kunicki
semanticscholar   +3 more sources

Membrane Glycoproteins in Cryopreserved Platelets

Vox Sanguinis, 1994
AbstractAlthough platelets stored by cryopreservation are effective in hemostasis, they acquire a number of functional defects during storage and preparation for transfusion. In addition to known acquired defects such as defective aggregation, decreased resistance to hypotonic shock, and disc‐spherocyte transformation, we have shown that cryopreserved ...
C. Afflerbach, Stein Holme, E. Werner, M. Owens   +3 more
openaire   +3 more sources

The role of platelet membrane glycoproteins Ib and IIb‐IIIa in platelet adherence to human artery subendothelium

British Journal of Haematology, 1986
Platelet adherence to human artery subendothelium in blood from eight normal subjects, four patients with Glanzmann's thrombasthenia (deficiency of platelet membrane glycoproteins IIb and IIIa: GPIIb‐IIIa), two patients with Bernard‐Soulier syndrome ...
K. Sakariassen, P. Nievelstein, B. Coller, J. Sixma   +3 more
semanticscholar   +1 more source

Platelet Aggregation By Membrane Glycoprotein I [PDF]

Thrombosis and Haemostasis, 1981
It has been recently shown that platelet membrane components, particularly glycoproteins, have a lectin activity, thus mediating an aggregation of platelets. To obtain further evidences for a crucial role of glycoproteins in an aggregation mechanism,we have investigated the possibility that membrane glycoprotein can directly induce an aggregation of ...
Y. Ikeda, Kiyoaki Watanabe, Keisuke Toyama, Makoto Handa, Y Yoshii, K Furihata, H Iri, M Yamamoto, K Sugiura, Michiyo Imai, Y Ando   +10 more
openaire   +1 more source