Journal of Education, Health and Sport, 2022 Antiphospholipid syndrome (APS) is a systemic autoimmune disease, which is characterized by thrombotic or obstetric events characterized by the presence in the blood of patients of a high titer of antibodies to natively charged membrane phospholipids ...
V. Savytskyi
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Platelet Membrane Glycoproteins: A Historical Review [PDF]
Seminars in Thrombosis and Hemostasis, 2014 The search for the components of the platelet surface that mediate platelet adhesion and platelet aggregation began for earnest in the late 1960s when electron microscopy demonstrated the presence of a carbohydrate-rich, negatively charged outer coat that was called the "glycocalyx." Progressively, electrophoretic procedures were developed that ...
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Suppressive effect of CORM-2 on LPS-induced platelet activation by glycoprotein mediated HS1 phosphorylation interference. [PDF]
PLoS ONE, 2013 In recent years, it has been discovered that septic patients display coagulation abnormalities. Platelets play a major role in the coagulation system.
Dadong Liu +5 more
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, 2014 A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
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Specific labelling of platelet membrane glycoproteins
FEBS Letters, 1980 The glycoproteins present on the platelet membrane are considered to be of great importance to platelet activities [ 1,2]. Few pathological platelet membrane glycoprotein abnormalities are known and ,usually they result in disturbance of aggregation.
Rotman, Avner +2 more
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Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. [PDF]
, 1989 Neural cell adhesion molecule (N-CAM) is a membrane glycoprotein expressed on neural and muscle tissues that is involved in homotypic adhesive interactions.
Bindl, J +3 more
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Antibodies against complement-regulatory proteins on platelets in immune thrombocytopenia
Platelets, 2017 In immune thrombocytopenia (ITP), antibodies reacting with platelet membrane glycoproteins (GP) mediate premature platelet cleavage, resulting in thrombocytopenia and therefore a risk of bleeding.
Ursula Unterberger +3 more
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Platelet Apoptosis Can Be Triggered Bypassing the Death Receptors
Clinical and Applied Thrombosis/Hemostasis, 2019 In nucleated cells, the extrinsic pathway of the programmed cell death (apoptosis) is triggered by interaction of death ligands of the tumor necrosis factor superfamily with the death receptors on external cell surface membrane.
Valery Leytin PhD +2 more
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Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]
, 2018 Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui +9 more
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Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]
, 2008 Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW +18 more
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