Results 61 to 70 of about 96,324 (329)
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Haematologica, 2011 Background Bernard-Soulier syndrome is a severe bleeding disease due to a defect of GPIb/IX/V, a platelet complex that binds the von Willebrand factor.
Anna Savoia +11 more
doaj +1 more source
Monkey Platelet Membrane Glycoproteins and Aggregation
Japanese Journal of Thrombosis and Hemostasis, 1991 The monkey is classified as close to the human and is important as an experimental animal. The present study, a comparison of human and monkey platelet membrane glycopreteins and aggregation, was undertaken.The major platelet membrane glycoprotein was similarly represented in humans and monkeys by SDS-polyacrylamide gel electrophoresis and PAS staining.
Terutoshi Kokawa +9 more
openaire +2 more sources
Studies on platelet membrane glycoproteins and platelet function during hemodialysis. [PDF]
Journal of the American Society of Nephrology, 1997 Hemodialysis only partially corrects the defects in platelet function associated with uremia. Platelet contact with the artificial surfaces of the dialysis filter during hemodialysis can itself cause platelet activation, degranulation, and loss of platelet membrane glycoproteins.
J A Sloand, E M Sloand
openaire +3 more sources
Advanced Science, EarlyView.Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu +16 more
wiley +1 more source
Advanced Science, EarlyView.Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley +1 more source
HematologyBackground: Bernard–Soulier syndrome (BSS) is a rare inherited macrothrombocytopenia, usually autosomal recessive, which is characterized by prolonged bleeding, thrombocytopenia, and abnormally large platelets.Methods: For more than 6 years, we ...
Senlin Zhang +7 more
doaj +1 more source
A fibronectin-binding glycoprotein from human platelet membranes [PDF]
Biochemical Journal, 1981 Fibronectin (‘cold-insoluble globulin’) has been suggested as a possible mediator of platelet adhesion. A fibronectin-binding protein as partially purified from washed solubilized human platelet membranes by affinity chromatography on fibronectin-Sepharose.
M. Sandbjerg Hansen, Inge Clemmensen
openaire +4 more sources
Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
Advanced Science, EarlyView.A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino +21 more
wiley +1 more source
Noncanonical effects of vasopressin in angiogenesis
Вавиловский журнал генетики и селекции, 2019 The molecular action of vasopressin depends on the localization of hormonal receptors. The basic physiological effects of vasopressin are manifested in the blood vasculature, renal inner medulla and brain.
I. I. Khegay
doaj +1 more source