Results 61 to 70 of about 29,930 (290)

Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease [PDF]

, 2003
Current teaching suggests that many patients are at risk for prolonged bleeding during and following invasive dental procedures, due to an acquired coagulopathy from systemic disease and/or from medications.
A Barber, AB Lumb, AD Kaye, AGG Turpie, AH Friedlander, AI Schafer, AM Ziffer, AS Gewirtz, AT Mailloux, BS Coller, C Kearon, CA Petruff, CH Mielke Jr., CL Norred, D Blinder, D Deykin, DB Petitti, DF Pawlak, DM Eisenberg, EM Hylek, F Catella-Lawson, FE Silverstein, G Palareti, G Russo, H Bagheri, H Ogiuchi, IW Scopp, J Gibson, J Harenberg, J Hirsh, J Hirsh, J Hirsh, J Leitch, J Marshall, JA Oates, JA Ware, JC O'Laughlin, JH Campbell, JN George, JN Saour, JR Vane, K Webster, L Bodner, L Mengle-Gaw, LC Tsen, LS Simon, M Akbarian, M Hurlen, M Levine, MH Eckman, MH Eckman, MJ Steinburg, MJ Troulis, MJ Wahl, MJ Wahl, MK Ang-Lee, MMW Koopman, N May, OR Beirne, P B Lockhart, P Devani, PC Amrein, PJ Sharis, R Benoliel, R De Caterina, R Hull, R Mulligan, R Mulligan, R Stern, RA Seymour, RE Alexander, RH White, RI Shorr, RT Weibert, S Cronberg, S Goldman, S H Pond, S Lippert, SC Cannegieter, SD Fihn, SE Lind, SE Lind, SI Rapaport, SJ Behrman, SR Cox, SS De Rossi, T Bandrowsky, TP Rooney, VA Ferraris, WR Bartle, WW Herman   +90 more
core   +1 more source

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

Advanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt, Sabrina Oerter, Evelin Reitenbach, Sabine Gätzner, Alevtina Höchner, Heinz‐Georg Jahnke, Jörg Piontek, Winfried Neuhaus, Andreas Brachner, Marco Metzger, Antje Appelt‐Menzel   +10 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

SARS‐CoV‐2 infection of companion animals in Egypt and its risk of spillover

Veterinary Medicine and Science, Volume 9, Issue 1, Page 13-24, January 2023., 2023
Graphical abstract depicts SARS‐CoV‐2 spillover in humans and their pet animals with common symptoms. Besides, it illustrates number of SARS‐CoV‐2‐infected cats and dogs with severity of respiratory signs. Abstract Background Reverse zoonoses occur because of interactions between humans and animals.
Mervat E. Hamdy, Ayman H. El‐Deeb, Naglaa M. Hagag, Momtaz A. Shahein, Namal P. M. Liyanage, Mohamed Shalaan, Hussein A. Hussein   +6 more
wiley   +1 more source

Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil

Revista Brasileira de Hematologia e Hemoterapia
Background: Immune thrombocytopenia is an immune disease characterized by thrombocytopenia and bleeding due to platelet antibodies against platelet membrane glycoproteins. Human platelet antigens are derived from polymorphisms of these glycoproteins. The
Julia Cavalcante do Carmo, Prissyla de Souza Klippel, Sabrine da Costa Cordeiro, Ângela Maria dos Santos Fernandes, Raquel Medeiros Pinto, Simone Schneider Weber, Cleiton Fantin   +6 more
doaj   +1 more source

Regenerative potential of autologous platelet-rich fibrin with and without amnion membrane in the treatment of Grade-II furcation defects: A clinicoradiographic study

Journal of Indian Society of Periodontology, 2018
Context: Platelet-rich fibrin (PRF), platelet concentrate composed of cytokines and structural glycoproteins trapped within polymerized fibrin meshwork, has the potential to accelerate healing of periodontal tissues.
Jaspreet Kaur, Shalu Chandna Bathla
doaj   +1 more source

Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen. [PDF]

, 1988
Cells of the rat neuronal line, PC12, adhere well to substrates coated with laminin and type IV collagen, but attach poorly to fibronectin. Adhesion and neurite extension in response to these extracellular matrix proteins are inhibited by Fab fragments ...
Damsky, CH, Reichardt, LF, Tomaselli, KJ
core   +1 more source

Pathophysiological mechanisms leading to low platelet count in immune thrombocytopenia [PDF]

, 2020
Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by the decrease in peripheral blood platelet count below 100 x 109/L, and an increased bleeding risk when thrombocytopenia drops below 30 x 109/L. The mechanisms leading to ITP
Goette, Nora Paula, Lev, Paola Roxana, Marta, Rosana Fernanda   +2 more
core   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

Advanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana, Samartha M C, Ashwath Acharya, Goutam Thakur, Manasa Nune, Vipul Agarwal   +5 more
wiley   +1 more source

Markers for internal neoplasia in the horse

Veterinary Medicine and Science, Volume 9, Issue 1, Page 132-143, January 2023., 2023
The measurement of tumour markers in horses should be performed only in risk groups or in patients with suspicious clinical/laboratory findings (paraneoplastic syndromes). The results should be interpreted with caution as many factors (e.g., young age, pregnancy and inflammation) affect their concentration or activity.
Karolina Drozdzewska, Heidrun Gehlen
wiley   +1 more source