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Platelet Transfusion

Current Opinion in Hematology
Purpose of review Platelet transfusions, used as prophylaxis or treatment for bleeding, are potentially life-saving. In many countries, demand for platelet transfusion is rising. Platelets are a limited and costly resource, and it is vital that they are used appropriately.
Agarwal A, Khan AI, Anwer F.
europepmc   +8 more sources

ABO-identical versus incompatible platelet transfusion in patients with intracranial hemorrhage. [PDF]

PLoS ONE
BackgroundPatients with spontaneous and traumatic intracranial hemorrhage (ICH) are frequently transfused platelets to treat thrombocytopenia, platelet function defects, and reverse antiplatelet drugs.
Lauren K Dunn, Emily Venner, Matthew Nguyen, Jose Perdomo Trejo, Zachary Holley, Bhiken I Naik, Jenna Khan, Michael Mazzeffi   +7 more
doaj   +2 more sources

Related donor platelet transfusion improves platelet transfusion refractoriness in hematological patients [PDF]

Frontiers in Medicine, 2023
ObjectiveTransfusion of HLA-matched platelets can reduce the effect of alloimmune responses on platelet transfusion efficacy; however, finding HLA-matched platelets in the population is nearly impossible. Almost all HLA-matched platelets from related are
Jing-Cheng Zhang, Li-Hong Ni, Yan Tu, Hui-Xian Hu   +3 more
doaj   +2 more sources

Mechanism and transfusion strategy of immunogenic platelet transfusion refractoriness

Zhongguo shuxue zazhi, 2022
Platelet transfusion is an irreplaceable method to treat patients with platelet reduction in Hematology Department and Oncology Department. However, immunogenic platelet transfusion refractoriness is a huge challenge to patients who require repeatedly ...
Juan SAI, Li TIAN
doaj   +1 more source

Transfusion effect of 0.5-dose of apheresis platelet in pediatric patients

Zhongguo shuxue zazhi, 2023
Objective To investigate the transfusion effect of 0.5-dose of apheresis platelet in pediatric patients. Methods A total of 195 children who underwent 0.5-dose platelet transfusion from August 2021 to June 2022 were enrolled, and the platelet count ...
Lijuan QIU, Zida ZHEN, Xiaoyan FU, Shuxuan MA   +3 more
doaj   +1 more source

Extent of transfusion support in a developing country in managing a bleeding acute myeloid leukemia patient with platelet transfusion refractoriness

Asian Journal of Transfusion Science, 2021
Conventional platelet transfusion may not be adequate to deal with platelet transfusion refractoriness (PTR), and therefore human leukocyte antigen (HLA) or human platelet antigen (HPA) matched and platelet crossmatch compatible units are recommended ...
Gayathiri K Chellaiya, Chandran K Nair, Vineetha Raghavan, R Jesu Pandian, Roshan Vinod, Mohandoss Murugesan   +5 more
doaj   +1 more source

Platelet Transfusion in Patients With Sepsis and Thrombocytopenia: A Propensity Score-Matched Analysis Using a Large ICU Database

Frontiers in Medicine, 2022
PurposeSepsis with thrombocytopenia is highly prevalent in critically ill intensive care unit (ICU) patients and is associated with adverse outcomes. Platelet transfusion is the primary treatment of choice. However, evidence for the beneficial effects of
Shuangjun He, Chenyu Fan, Jun Ma, Chao Tang, Yi Chen   +4 more
doaj   +1 more source

Efficacy of apheresis platelet transfusion in 310 patients with haematological diseases

Zhongguo shuxue zazhi, 2023
Objective To observe the effect of platelet transfusion in inpatients with haematological diseases, analyze the possible causes of platelet transfusion refractoriness (PTR), in order to further improve the efficacy of platelet transfusion.
Shisong YOU, Liqi LU, Qun CAI, Xiaomei LI, Xiulan HUANG, Jingwei ZHANG   +5 more
doaj   +1 more source

Establishment and evaluation of predictive models of platelet transfusion effect in multi-center tumor patients

Zhongguo shuxue zazhi, 2023
Objective To study the platelet transfusion predictive models in tumor patients and evaluate its application effect. Methods A retrospective study was conducted on 944 tumor patients, including 533 males and 411 females who received platelet transfusion ...
Gang ZHAO, Fan GUO, Qing LI, Yihua XIE, Jun LI   +4 more
doaj   +1 more source

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source