Results 61 to 70 of about 130,205 (352)

Platelet transfusion for cancer secondary thrombocytopenia: Platelet and cancer cell interaction

Translational Oncology, 2021
Chemoradiotherapy and autoimmune disorder often lead to secondary thrombocytopenia in cancer patients, and thus, platelet transfusion is needed to stop or prevent bleeding. However, the effect of platelet transfusion remains controversial for the lack of
Juan Wang, Pan Zhou, Yunwei Han, Hongwei Zhang   +3 more
doaj   +1 more source

Penatalaksanaan Prabedah Penderita Dengan Trombositopenia [PDF]

, 2009
Bleeding, either medical or surgical bleeding, remains an important issue in surgery. Therefore, complete blood count and bleeding time are routinely checked in patients undergoing surgical procedures.
Vera, V. (Vera)
core  

Leucoreduction of blood components. an effective way to increase blood safety? [PDF]

, 2015
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria, Facco, Giuseppina, Grazzini, Giuliano, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +6 more
core   +1 more source

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

American Journal of Hematology, EarlyView.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs, Elizabeth A. Abels, Brian D. Adkins, Garrett S. Booth, Victoria Costa, Sheharyar Raza, Michelle Simon, Jennifer S. Woo, Allison P. Wheeler   +8 more
wiley   +1 more source

Effectiveness of Pooled Platelet Transfusion in Concordant and Discordant Groups among Dengue Patients [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Dengue affects more than 50 million people per year and is one of the most common causes of severe thrombocytopaenia. Thrombocytopaenia is a common complication of dengue and other viral fevers apart from malaria, typhoid, leptospirosis,
Amoolya Bhat, Vijaya Chowdappa, Smita Surendra Masamatti   +2 more
doaj   +1 more source

The use of fibrinogen concentrate for the management of trauma-related bleeding. A systematic review and meta-analysis [PDF]

, 2017
Haemorrhage following injury is associated with significant morbidity and mortality. The role of fibrinogen concentrate in trauma-induced coagulopathy has been the object of intense research in the last 10 years and has been systematically analysed in ...
Franchini, Massimo, Liumbruno, Giancarlo M., Marano, Giuseppe, Marietta, Marco, Mengoli, Carlo, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Proteomic Analysis of Golden Sputum Reveals Pulmonary Complement Activation During Acute Chest Syndrome in Children With Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Acute chest syndrome (ACS) is one of the most common severe complications of sickle cell disease (SCD). In recent years, a major role of inflammation and innate immunity has been evidenced, but ACS pathophysiology remains incompletely understood, and therapeutic options are limited.
Slimane Allali, Nabiha Sbeih, Rachel Rignault‐Bricard, Johanna Bruce, Morgane Le Gall, Claire Heilbronner, Noemie de Cacqueray, Sofia Angyalosy, Melissa Taylor, Joséphine Brice, Mariane de Montalembert, Martina Bevacqua, Emilie‐Fleur Gautier, Olivier Hermine, Thiago Trovati Maciel   +14 more
wiley   +1 more source

Platelet antibodies in immune thrombocytopenia and related conditions

Journal of Laboratory Medicine, 2020
Platelet autoantibodies are a common finding in immune thrombocytopenia (ITP) and in rare cases of antibody-mediated platelet function (“acquired thrombasthenia”).
Kiefel Volker
doaj   +1 more source

A randomized cross‐over study of cryopreserved platelets in prophylactic transfusions of thrombocytopenic patients [PDF]

, 2023
Ai Leen Ang, Linda Seo Hwee Gan, Tertius Tuy, Chieh Hwee Ang, Chuen Wen Tan, Hwee Huang Tan, Pei Huey Shu, Qingxiang Zhang, Yang Cao, Rajesh Babu Moorakonda, Yogesh Pokharkar, Jia Jie Lu   +11 more
openalex   +1 more source

Hetrombopag Added to Cyclosporine as the First‐Line Treatment for Patients With Non‐Severe Aplastic Anemia: A Phase 2 Multicenter Trial

American Journal of Hematology, EarlyView.
ABSTRACT Non‐severe aplastic anemia (NSAA) is a heterogeneous bone marrow failure syndrome with limited standardized treatment options. Cyclosporine A (CsA) monotherapy often yields suboptimal responses, highlighting an unmet clinical need for more effective therapies.
Lele Zhang, Ruonan Li, Qian Liang, Weiwang Li, Hong Pan, Zhen Gao, Liwei Fang, Jingyu Zhao, Xiao Yu, Zhexiang Kuang, Neng Nie, Jianping Li, Jinbo Huang, Xin Zhao, Meili Ge, Yizhou Zheng, Jun Li, Hong Zhang, Jun Shi   +18 more
wiley   +1 more source