Results 1 to 10 of about 3,422 (217)

Related donor platelet transfusion improves platelet transfusion refractoriness in hematological patients [PDF]

Frontiers in Medicine, 2023
ObjectiveTransfusion of HLA-matched platelets can reduce the effect of alloimmune responses on platelet transfusion efficacy; however, finding HLA-matched platelets in the population is nearly impossible. Almost all HLA-matched platelets from related are
Jing-Cheng Zhang, Li-Hong Ni, Yan Tu, Hui-Xian Hu   +3 more
doaj   +4 more sources

Platelet Transfusion Refractoriness

Plasmatology
Platelet transfusion refractoriness (PTR) is a conditioikb1n where platelet counts fail to increase adequately in several transfusions, often found in hemato-oncological situations.
Anna Mira Lubis MD, Muhammad Orri Baskoro MD, Amirah Yasmin MD   +2 more
doaj   +3 more sources

Prevention and Management of Platelet Transfusion Refractoriness [PDF]

Vox Sanguinis, 1999
AbstractPlatelet transfusion refractoriness is a major complication of long‐term platelet supportive care. Refractoriness may lead to fatal bleeding complications in thrombocytopenic patients. Major factors involved are factors related to the clinical condition of the patient as well as HLA alloimmunisation. Non‐alloimmune factors may occur in up to 80%
V.M.J. Novotný
openalex   +4 more sources

Identification of platelet refractoriness in oncohematologic patients [PDF]

Clinics, 2011
OBJECTIVES: To identify the occurrence and the causes of platelet refractoriness in oncohematologic patients. INTRODUCTION: Platelet refractoriness (unsatisfactory post-transfusion platelet increment) is a severe problem that impairs the treatment of ...
Aline Aparecida Ferreira, Roberto Zulli, Sheila Soares, Vagner de Castro, Helio Moraes-Souza   +4 more
doaj   +6 more sources

Management of Alloimmunized, Refractory Patients in Need of Platelet Transfusions [PDF]

Vox Sanguinis, 1997
immunization in patients whohave been previously immunized by pregnan-cy or transfusion is not prevented. Neither canimmunization against platelet-specific al-loantigens be prevented by removing leuco-cytes from platelet concentrates, but platelet-specific antibodies seem to occur mainly inpatients who develop HLA class I antibodies.Not all patients ...
Michael Murphy, R. Curtis, A. H. Waters
  +8 more sources

The use of splenectomy to manage platelet transfusion refractoriness due to anti-human leukocyte antibodies in allogeneic stem cell transplantation

Pediatric Reports, 2016
In patients undergoing hematopoietic stem cell transplantation (HSCT), refractoriness to platelet transfusion has been associated with graft failure, delayed engraftment, early mortality and decreased overall survival.
Margherita Mauro, Francesco Camoglio, Pierluigi Piccoli, Massimiliano De Bortoli, Rita Balter, Anna Pegoraro, Simone Cesaro   +6 more
doaj   +3 more sources

Evaluation of Human Leucocyte Antigen Mediated Platelet Transfusion Refractoriness and Platelet Crossmatching Assay in Patients with Hematologic Disorders

Oman Medical Journal, 2022
Objectives: Platelet refractoriness complicates the platelet transfusion, which is essential for managing thrombocytopenia in patients with hematological disorders. It is associated with adverse clinical outcomes and increased health care costs.
Wafaa A. Neanaey, Akram A. Deghady, Dalia A. Nafea, Nada M. Fahmy, Asmaa M. Gouda   +4 more
doaj   +2 more sources

Prevalence of platelet reactive antibodies in patient′s refractory to platelet transfusions

Asian Journal of Transfusion Science, 2014
Introduction & Aims: Though platelet transfusions have greatly reduced the incidence of major haemorrhagic complications associated with the management of haematological and oncological disorders, refractoriness to infused platelets becomes a major ...
Nitin Agarwal, Kabita Chatterjee, Alok Sen, Praveen Kumar   +3 more
doaj   +4 more sources

Transfusão de plaquetas: do empirismo ao embasamento científico Platelet transfusion: from empiricism to scientific evidence [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2010
Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion ...
Aline A. Ferreira, Sheila Soares, Vagner de Castro, Helio Moraes-Souza   +3 more
doaj   +3 more sources

Refractoriness to platelet transfusion after single-donor consecutive platelet transfusions and its relationship to platelet antibodies [PDF]

Journal of Korean Medical Science, 1988
In thirty patients with acute leukemia and severe aplastic anemia receiving random single donor platelet transfusions, the development of refractoriness by consecutive platelet transfusions with cytapheresis and its relationship to the appearance of anti-platelet antibodies were investigated.
Munho Lee, Byoung Kook Kim, Seonyang Park, Cheolwon Suh, Myoung Hee Park, Myong Joon Cho   +5 more
openalex   +5 more sources