Results 11 to 20 of about 5,003 (295)

Avatrombopag for the salvage treatment of platelet transfusion refractoriness [PDF]

Therapeutic Advances in Hematology
Background: Platelet transfusion refractoriness (PTR) is a life-threatening and intractable condition in hematological patients. Thrombopoietin receptor agonists such as avatrombopag promote platelet production and modulate immune intolerance.
Yuehong Qin, Yu Wang, Yujiao Zhang, Yingying Jiao, Jieyu Ye   +4 more
doaj   +4 more sources

Extent of transfusion support in a developing country in managing a bleeding acute myeloid leukemia patient with platelet transfusion refractoriness

Asian Journal of Transfusion Science, 2021
Conventional platelet transfusion may not be adequate to deal with platelet transfusion refractoriness (PTR), and therefore human leukocyte antigen (HLA) or human platelet antigen (HPA) matched and platelet crossmatch compatible units are recommended ...
Gayathiri K Chellaiya, Chandran K Nair, Vineetha Raghavan, R Jesu Pandian, Roshan Vinod, Mohandoss Murugesan   +5 more
doaj   +2 more sources

Anti-HLA Class I alloantibodies in platelet transfusion refractoriness: From mechanisms and determinants to therapeutic prospects [PDF]

Frontiers in Immunology, 2023
Patients with hematological disorders and severe thrombocytopenia require extensive and iterative platelet transfusion support. In these patients, platelet transfusion refractoriness represents a serious adverse transfusion event with major outcomes for ...
Adèle Couvidou, Adèle Couvidou, Adèle Couvidou, Adèle Couvidou, Gabriel Rojas-Jiménez, Gabriel Rojas-Jiménez, Gabriel Rojas-Jiménez, Gabriel Rojas-Jiménez, Arnaud Dupuis, Arnaud Dupuis, Arnaud Dupuis, Arnaud Dupuis, Blandine Maître, Blandine Maître, Blandine Maître, Blandine Maître   +15 more
doaj   +2 more sources

Prevalence, Risk Factors, and Outcomes of Platelet Transfusion Refractoriness in Critically Ill Patients: A Retrospective Cohort Study [PDF]

Critical Care Research and Practice, 2021
Background. Refractoriness to platelet transfusion is an understudied phenomenon in critically ill patients. Our objective was to evaluate the prevalence, risk factors, and clinical outcomes of platelet refractoriness among patients in a tertiary-care ...
Saeed Arabi, Abdullah O. Almahayni, Abdulrahman A. Alomair, Emad M. Masuadi, Moussab Damlaj, Hasan M. Al-Dorzi   +5 more
doaj   +2 more sources

Evaluation and management of platelet transfusion refractoriness [PDF]

Blood Research, 2022
Platelet transfusion refractoriness (PTR), in which platelet counts do not increase after transfusion, occurs in many patients receiving platelet transfusions. PTR is a clinical condition that can harm patients. The causes of PTR can be divided into two types: immune and non-immune. Most cases of PTR are non-immune. Among immune causes, the most common
Youk, Hee-Jeong, Hwang, Sang-Hyun, Oh, Heung-Bum, Ko, Dae-Hyun   +3 more
openaire   +3 more sources

Prevalence of risk factors for platelet transfusion refractoriness in multitransfused hemato-oncological patients at tertiary care center in North India

Asian Journal of Transfusion Science, 2015
Background: This study was designed to determine the prevalence and assess the risk factors responsible for platelet transfusion refractoriness in hemato-oncological patients. Materials and Methods: The study included 30 patients.
Vijay Kumawat, Ratti Ram Sharma, Pankaj Malhotra, Neelam Marwaha   +3 more
doaj   +2 more sources

First platelet transfusion refractoriness in a patient with acute myelocytic leukemia: A case report [PDF]

World J Clin Cases, 2023
Sheng-Ke Tu, Hongjie Fan, Zi-Wei Shi, Xiaolan Li, Min Li, Kui Song   +5 more
openalex   +2 more sources

Severe platelet transfusion refractoriness after thoracoabdominal aneurysm repair [PDF]

Journal of Vascular Surgery Cases and Innovative Techniques
Severe thrombocytopenia after thoracoabdominal aortic aneurysm repair poses a significant clinical risk in the immediate postoperative period.
Claire M. Motyl, MD, S. Danielle Phillips, AGACNP-BC, RNFA, Jori E. May, MD, Adam W. Beck, MD   +3 more
doaj   +2 more sources

Platelet HLA gene bank digital matching technology for platelet transfusion refractory patients with malignant tumors: a case report [PDF]

Frontiers in Oncology
The platelet human leucocyte antigen (HLA) gene bank contains the genetic information of HLA loci in a large number of blood donors. Currently, the most effective treatment for platelet transfusion refractoriness (PTR) is to evaluate the probability of ...
Xiang Gao, Jianhua Li, Xiuwen Ni, Lijun Wang, Peilin Hu, Xiaowei Zhu   +5 more
doaj   +2 more sources

PLATELET TRANSFUSION REFRACTORINESS ASSOCIATED WITH PLASMA PROTEINS [PDF]

British Journal of Haematology, 1993
Joanna M. Heal, Neil Blumberg
openalex   +3 more sources