Results 1 to 10 of about 433,397 (321)
TSST-1 protein exerts indirect effect on platelet activation and apoptosis
Thrombocytopenia or platelet dysfunction is a risk factor for severe infection. Staphylococcus aureus (S. aureus) releases a variety of virulence factors especially toxic shock syndrome toxin 1 (TSST-1), which may cause toxic shock syndrome. S.
Min Guo+6 more
doaj +1 more source
Modeling of Polymer Clay Nanocomposite for a Multiscale Approach [PDF]
The mechanical property enhancement of polymer reinforced with nano-thin clay platelets (of high aspect ratio) is associated with a high polymer-filler interfacial area per unit volume. The ideal case of fully separated (exfoliated) platelets is generally difficult to achieve in practice: a typical nanocomposite also contains multilayer stacks of ...
arxiv +1 more source
Circulating microRNAs as biomarkers and mediators of platelet activation
Platelets are essential mediators of physiological hemostasis and pathological thrombosis. Currently available tests and markers of platelet activation did not prove successful in guiding treatment decisions for patients with cardiovascular disease ...
Clemens Gutmann, Manuel Mayr
doaj +1 more source
A megakaryocyte with no platelets: Anti-platelet antibodies, apoptosis, and platelet production
Primary immune thrombocytopenia (ITP) and drug-induced thrombocytopenia (DITP) are disorders caused primarily by the presence of anti-platelet auto-antibodies (Abs). Hematologists have traditionally seen thrombocytopenia as the result of increased destruction of Ab-coated platelets by the reticuloendothelial system.
Feng Yan, Jose Perdomo, Beng H. Chong
openaire +2 more sources
Immune thrombocytopenia (ITP) is a condition that is distinct from thrombosis with thrombocytopenia syndrome (TTS) that may also occur after coronavirus disease 2019 (COVID-19) vaccinations.
Sheng-Chieh Chou+6 more
doaj +1 more source
The utility of flow cytometric platelet forward scatter as an alternative to mean platelet volume
The use of mean platelet diameter (MPD) to classify inherited thrombocytopenia (IT) has been demonstrated in several studies. Alternatively, the mean platelet volume (MPV) may be used, but in macrothrombocytopenia this may not be available.
David Connor+12 more
doaj +1 more source
Anomalous Platelet Transport & Fat-Tailed Distributions [PDF]
The transport of platelets in blood is commonly assumed to obey an advection-diffusion equation. Here we propose a disruptive view, by showing that the random part of their velocity is governed by a fat-tailed probability distribution, usually referred to as a L\'evy flight.
arxiv
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by induction of mRNA degradation and post-transcriptional repression of gene expression.
Zofia Wicik+9 more
doaj +1 more source
Impaired platelet production is a mechanism of immune thrombocytopenia (ITP). Morphological abnormalities of megakaryocytes (MKs) are sometimes observed in this disease.
Ondine Walter+15 more
doaj +1 more source
Effect of tube diameter and capillary number on platelet margination and near-wall dynamics [PDF]
The effect of tube diameter $D$ and capillary number $Ca$ on platelet margination in blood flow at $\approx 37\%$ tube haematocrit is investigated. The system is modelled as three-dimensional suspension of deformable red blood cells and nearly rigid platelets using a combination of the lattice-Boltzmann, immersed boundary and finite element methods ...
arxiv +1 more source