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Platelets and galectins [PDF]

open access: yesAnnals of translational medicine, 2014
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core   +5 more sources

Therapeutic potential of adult platelets and cord blood platelets in future clinical directions

open access: yesJournal of Medical and Scientific Research, 2023
Platelet rich plasma (PRP) is currently obtaining a natural concentration of autologous growth factors, and is used in different medical conditions. This review is aimed to establish several treatment options using adult PRP and scope of the therapeutic ...
Bezawada SR, Velluri V, Darapuneni RC
doaj   +1 more source

Lyophilized platelets inhibit platelet aggregation with simultaneous paradoxical promotion of platelet adhesion

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Lyophilized platelets have been explored as a potential hemostatic agent due to their long-term ambient storage capabilities that make them readily available in various scenarios.
Brian Schnoor, Anne-Laure Papa
doaj   +1 more source

Platelets and Platelet Phosphatides in Uremia [PDF]

open access: yesBlood, 1960
Abstract 1. The platelets of 20 uremic subjects were studied, utilizing the following procedures; phase platelet count, serum prothrombin time, thromboplastin generation test with evaluation of plasma, serum, and platelet reagents. 2.
Harris L. Ullman   +2 more
openaire   +3 more sources

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

open access: yes, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle   +2 more
core   +1 more source

Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]

open access: yes, 2002
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E.   +3 more
core   +1 more source

Role of P-selectin in platelet sequestration in pulmonary capillaries during endotoxemia [PDF]

open access: yes, 2006
Background: There is growing evidence that platelets accumulate in the lung and contribute to the pathogenesis of acute lung injury during endotoxemia.
Alwin Eduard Goetz   +37 more
core   +1 more source

Platelets and Anti-platelet Therapy

open access: yesJournal of Pharmacological Sciences, 2003
Platelets play a central role in the hemostatic process and consequently are similarly involved in the pathological counterpart, thrombosis. They adhere to various subendothelial proteins, exposed either by injury or disease, and subsequently become activated by the thrombogenic surface or locally produced agonists.
Sara J. Israels, Archibald McNicol
openaire   +5 more sources

BLOOD PLATELETS AS ACTIVATORS AND REGULATORS OF INFLAMMATORY AND IMMUNE REACTIONS. PART 1. BASIC CHARACTERISTICS OF PLATELETS AS INFLAMMATORY CELLS

open access: yesМедицинская иммунология, 2018
Platelets are the smallest blood cells, and yet their total volume and surface area exceed those of all types of leukocytes combined. Platelets are produced by the bone marrow megakaryocytes and megakaryocytes in the lung microvessels.
N. B. Serebryanaya   +3 more
doaj   +1 more source

Protocol for Murine/Mouse Platelets Isolation and Their Reintroduction in vivo

open access: yesBio-Protocol, 2017
Platelets and coagulation have long been known to be essential for metastasis in experimental models. In order to study the interactions between tumor cells, platelets and endothelium, we have adapted methods used in coagulation research for the ...
Jae Im, Ruth Muschel
doaj   +1 more source

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