Results 241 to 250 of about 790,517 (360)

Native C3 is activated without proteolytic cleavage by transformation to C3(H₂O) on phospholipid-scrambled cell membranes. [PDF]

Front Immunol
Eikrem D, Manivel VA, Whittaker J, Hamad OA, Mohlin C, Adler A, Dührkop C, Ebert R, Teramura Y, Ekdahl KN, Fromell K, Nilsson B.   +11 more
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

RABBIT PYROGEN TEST STUDY OF INFUSIBLE PLATELET MEMBRANE AS A PLATELET SUBSTITUTE FOR BLOOD TRANSFUSION

, 2014
Setareh Gholizadeh, Shirzad Nasiri, Siavash Ahmadi‐Noorbakhsh, Esmat Mirabzadeh, Saeid Rivandi   +4 more
openalex   +2 more sources

Resistance exercise exerts anti-hypertensive effects and downregulates NTPDase/CD39 and ecto-5'-nucleotidase/CD73 expression in patients with chronic kidney disease undergoing hemodialysis. [PDF]

Purinergic Signal
Dalagnol AMK, Franscescon F, Bianchini MC, Puhle JG, da Silva KET, Santos HM, de Oliveira Maciel SFV, de Resende E Silva DT.   +7 more
europepmc   +1 more source

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Critical evaluation of platelet size as a prognostic biomarker in colorectal cancer across multiple treatment settings: a retrospective cohort study

, 2019
Dominik A. Barth, Julia Riedl, Florian Posch, Maria Anna Smolle, Anne-Katrin Kasparek, Tobias Niedrist, Joanna Szkandera, Herbert Stöger, Max Pichler, Michael Stotz, Armin Gerger   +10 more
openalex   +1 more source

Reversible formation of von-Willebrand-factor-platelet aggregates in microvascular blood flow. [PDF]

PNAS Nexus
Topuz A, Hoore M, Gompper G, Fedosov DA.
europepmc   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

High-throughput combinatorial screening of antiplatelet drugs for personalized medicine. [PDF]

Microsyst Nanoeng
Wang C, Zhu W, Zhu J, Gao T, Jiang Z, Zhang T, Chen L, Zhang J, Liu Y, Chang ACY.   +9 more
europepmc   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source