Results 261 to 270 of about 771,873 (354)

Proteomic insights into platelet dysregulation and pathogenic mechanisms of chronic thromboembolic pulmonary hypertension. [PDF]

J Transl Med
Sun L, Li H, Li Y, Li X, Tian H, Liu J, Liu M, Wang J, Huang Q, Zhang Z, Ji X, Xi L, Li K, Li Y, Niu X, Duo M, Zou B, Wen J, Li J, Miao R, Xie W, Xu S, Yang P, Zhai Z.   +23 more
europepmc   +1 more source

Protein Synthesis by Human Platelets

, 1967
Andrew L. Warshaw, Leonard Laster, N. Raphael Shulman   +2 more
openalex   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

MECHANISM OF 5-HYDROXYTRYPTAMINE RELEASE INDUCED BY BACTERIAL LIPOPOLYSACCHARIDE FROM BLOOD PLATELETS

, 1968
Isami Kuruma, Hiroshi Takagi
openalex   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

Posttransfusion recovery, quality, and metabolism of short- and long-term stored platelets during controlled inflammation. [PDF]

Blood Adv
van Wonderen SF, van Baarle FLF, Phelp PG, Bulle EB, Argabright A, de Bruin S, Tuip-de Boer AM, Polet CA, van Amstel RBE, Lim EHT, Schenk J, Peters AL, van Bruggen R, Reisz JA, Vermeulen C, Klei TRL, Biemond BJ, Müller MCA, D'Alessandro A, Vlaar APJ.   +19 more
europepmc   +1 more source

Loss of Fibronectin Fiber Tension in Glioblastoma is Associated with Microvascular Proliferations and Immune Cell Infiltration

Advanced Science, EarlyView.
Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani, Isabel Gerber, Arnaud Mieville, Katrin Frauenknecht, Theoni Maragkou, Tibor Hortobagyi, Viola Vogel   +6 more
wiley   +1 more source

May-Hegglin Anomaly (MHA): A Rare Platelet Disorder Presenting for Coronary Artery Bypass Grafting, Managed With Post-bypass Administration of Platelets and Desmopressin. [PDF]

Cureus
Bond JA, Statler A, Bozek J, Abbas Khan MA, Ellison MB.   +4 more
europepmc   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Comparison of Conventional Dose Versus Superdose Platelet-Rich Plasma for Knee Osteoarthritis: Response. [PDF]

Orthop J Sports Med
Patel S, Thami T, Gahlaut S, Chouhan DK, Dhillon M.   +4 more
europepmc   +1 more source