Results 261 to 270 of about 790,517 (360)

The Relationship Between Mean Platelet Volume (MPV) and Cardiac Troponin I (cTnI) Levels and Mortality in Patients with Ischemic Stroke

, 2019
Öner Bozan
openalex   +2 more sources

Successful Use of Recombinant Tissue Plasminogen Activator in an Extremely Low Birth Weight Premature Infant for the Resolution of Multiple Thrombi. [PDF]

AJP Rep
Mody K, Wade C, Micetic B, Vernon M, Wade N.   +4 more
europepmc   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human platelets

, 1989
Shunsuke Nakamura, Hirohei Yamamura
openalex   +1 more source

Apheresis platelets modulate myeloid dendritic cell immune responses. [PDF]

Sci Rep
Ding M, Li Y, Xiao Q, Wang M, Feng X.
europepmc   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Importance of homogenization in platelet-rich plasma researches

, 2018
Ali Gökkaya, Metin Görğü, Ertuğrul Karanfil, Ertuğrul Karanfil, Jehat Kızılkan, Rıza Doğan   +5 more
openalex   +2 more sources

Potential Mechanisms Underlying Bleeding During Infection With Hemorrhagic Fever Viruses. [PDF]

Arterioscler Thromb Vasc Biol
Perkins MV, Mackman N.
europepmc   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Proprotein Convertase Subtilisin/Kexin Type 9 Induces Platelet-Derived Transforming Growth Factor-<i>β</i> to Promote Myocardial Fibrosis After Myocardial Infarction. [PDF]

Hum Mutat
Wang Q, Huang W, Xia D, Wang F, Nair S.
europepmc   +1 more source