Results 301 to 310 of about 790,517 (360)
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The Lancet, 2000
Platelets, derived from megakaryocyte cytoplasm, have a critical role in normal haemostasis, and in thrombotic disorders. The development of megakaryocytes is controlled by thrombopoietin, which binds to c-mpl on the surface of platelets and megakaryocytes.
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Platelets, derived from megakaryocyte cytoplasm, have a critical role in normal haemostasis, and in thrombotic disorders. The development of megakaryocytes is controlled by thrombopoietin, which binds to c-mpl on the surface of platelets and megakaryocytes.
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Nursing Clinics of North America, 2016
Antithrombotic medications have become standard of care for management of acute coronary syndrome. Platelet adhesion, activation, and aggregation are essential components of platelet function; platelet-inhibiting medications interfere with these components and reduce incidence of thrombosis.
Megan M, Shifrin, S Brian, Widmar
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Antithrombotic medications have become standard of care for management of acute coronary syndrome. Platelet adhesion, activation, and aggregation are essential components of platelet function; platelet-inhibiting medications interfere with these components and reduce incidence of thrombosis.
Megan M, Shifrin, S Brian, Widmar
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Blood Platelets and Platelet Transfusions
Archives of Internal Medicine, 1961The application of quantitative biological and biochemical methods to the study of the blood platelets has led to revolutionary developments in our understanding of these elusive structures. 1 Until recently platelets were often regarded as non-cellular in nature, although it has long been known that they are of cellular origin.
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British Journal of Haematology, 1977
SUMMARY.Autoimmunity to platelets was looked for by complement fixation, antiglobulin consumption, transformation and migrationâinhibition techniques. Only the migrationâinhibition method gave consistently positive results. The test was positive in nine out of 14 patients with idiopathic thrombocytopenic purpura and all five patients with glandular ...
I, Chanarin +3 more
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SUMMARY.Autoimmunity to platelets was looked for by complement fixation, antiglobulin consumption, transformation and migrationâinhibition techniques. Only the migrationâinhibition method gave consistently positive results. The test was positive in nine out of 14 patients with idiopathic thrombocytopenic purpura and all five patients with glandular ...
I, Chanarin +3 more
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Platelet Formation, Platelet Density and Platelet Ageing
1990Microscopic examination of both platelets and megakaryocytes shows them to vary widely in size and ultrastructure. This structural diversity was noted by early investigators (Bunting 1909) and interest in its origin and significance has continued to the present day.
K. G. Chamberlain +2 more
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Mass Spectrometry Reviews, 2011
AbstractPlatelets are small cell fragments, produced by megakaryocytes, in the bone marrow. They play an important role in hemostasis and diverse thrombotic disorders. They are therefore primary targets of antithrombotic therapies. They are implicated in several pathophysiological pathways, such as inflammation or wound repair.
Zufferey Bakos, Anne +4 more
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AbstractPlatelets are small cell fragments, produced by megakaryocytes, in the bone marrow. They play an important role in hemostasis and diverse thrombotic disorders. They are therefore primary targets of antithrombotic therapies. They are implicated in several pathophysiological pathways, such as inflammation or wound repair.
Zufferey Bakos, Anne +4 more
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Clinics in Laboratory Medicine, 1996
The proper diagnosis of patients with immune-mediated thrombocytopenias can be accomplished by using the advances made in the field of platelet serology. These techniques range from solid phase red cell adherence to sequencing platelet antigen amino acids by polymerase chain reaction.
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The proper diagnosis of patients with immune-mediated thrombocytopenias can be accomplished by using the advances made in the field of platelet serology. These techniques range from solid phase red cell adherence to sequencing platelet antigen amino acids by polymerase chain reaction.
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Pediatrics In Review, 2020
After vascular injury and exposure of subendothelial matrix proteins to the intravascular space, mediators of hemostasis are triggered and allow for clot formation and restoration of vascular integrity. Platelets are the mediators of primary hemostasis, creating a platelet plug and allowing for initial cessation of bleeding.
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After vascular injury and exposure of subendothelial matrix proteins to the intravascular space, mediators of hemostasis are triggered and allow for clot formation and restoration of vascular integrity. Platelets are the mediators of primary hemostasis, creating a platelet plug and allowing for initial cessation of bleeding.
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Current Opinion in Hematology, 2003
COAT platelets are a recently described subpopulation of cells resulting from simultaneous activation with collagen and thrombin. The complete process by which COAT platelets are produced is still not clear, although significant recent progress has been made.COAT platelets retain several procoagulant proteins on their surface by a previously ...
Robert, Szasz, George L, Dale
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COAT platelets are a recently described subpopulation of cells resulting from simultaneous activation with collagen and thrombin. The complete process by which COAT platelets are produced is still not clear, although significant recent progress has been made.COAT platelets retain several procoagulant proteins on their surface by a previously ...
Robert, Szasz, George L, Dale
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2013
Platelets are cell fragments which circulate in blood. They are of pivotal importance in blood clot formation, affecting thrombosis and haemostasis. By rapidly altering the activation and expression of surface receptors, platelets are able to quickly undergo structural and phenotypic changes in response to stimulation, such as collagen exposure on ...
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Platelets are cell fragments which circulate in blood. They are of pivotal importance in blood clot formation, affecting thrombosis and haemostasis. By rapidly altering the activation and expression of surface receptors, platelets are able to quickly undergo structural and phenotypic changes in response to stimulation, such as collagen exposure on ...
openaire +2 more sources