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Platelets and platelet disorders in Africa
Baillière's Clinical Haematology, 1992Blood platelets, which are known to play important roles in normal vertebrate biology, are influenced by a variety of factors, the majority of which are acquired. In this chapter, attention is drawn to the need to re-examine one of the old accepted values in haematology, the normal platelet count.
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Blood Platelets and Platelet Transfusions
Archives of Internal Medicine, 1961The application of quantitative biological and biochemical methods to the study of the blood platelets has led to revolutionary developments in our understanding of these elusive structures. 1 Until recently platelets were often regarded as non-cellular in nature, although it has long been known that they are of cellular origin.
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European Journal of Clinical Investigation, 2013
AbstractVascular injury is the initial manifestation of inflammation resulting in the recruitment and activation of various cell types. The integrity of the vascular wall is monitored by platelets that become activated in the presence of exposed subendothelium.
Habets, K.L.L. +2 more
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AbstractVascular injury is the initial manifestation of inflammation resulting in the recruitment and activation of various cell types. The integrity of the vascular wall is monitored by platelets that become activated in the presence of exposed subendothelium.
Habets, K.L.L. +2 more
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Thrombosis Research, 2014
The pathogenesis of migraine, the third most frequent disease worldwide, is complex and multifaceted. Recent evidence suggests that this condition should be considered as a primary neurovascular disorder. The pathogenesis is sustained by a relative reduction of cerebral blood flow, which is then followed by reactive hyperaemia, sterile inflammation and
DANESE, Elisa +2 more
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The pathogenesis of migraine, the third most frequent disease worldwide, is complex and multifaceted. Recent evidence suggests that this condition should be considered as a primary neurovascular disorder. The pathogenesis is sustained by a relative reduction of cerebral blood flow, which is then followed by reactive hyperaemia, sterile inflammation and
DANESE, Elisa +2 more
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The Lancet, 2000
Platelets, derived from megakaryocyte cytoplasm, have a critical role in normal haemostasis, and in thrombotic disorders. The development of megakaryocytes is controlled by thrombopoietin, which binds to c-mpl on the surface of platelets and megakaryocytes.
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Platelets, derived from megakaryocyte cytoplasm, have a critical role in normal haemostasis, and in thrombotic disorders. The development of megakaryocytes is controlled by thrombopoietin, which binds to c-mpl on the surface of platelets and megakaryocytes.
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2013
Platelet counting is a daily basic hematological analysis of crucial interest in many clinical situations. Historical manual techniques (phase-contrast microscopy) have been replaced by automated techniques (impedance or optical analyzers) more rapid and precise.
Salignac, Sylvain +3 more
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Platelet counting is a daily basic hematological analysis of crucial interest in many clinical situations. Historical manual techniques (phase-contrast microscopy) have been replaced by automated techniques (impedance or optical analyzers) more rapid and precise.
Salignac, Sylvain +3 more
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Platelet Formation, Platelet Density and Platelet Ageing
1990Microscopic examination of both platelets and megakaryocytes shows them to vary widely in size and ultrastructure. This structural diversity was noted by early investigators (Bunting 1909) and interest in its origin and significance has continued to the present day.
M. Tong +2 more
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Vox Sanguinis, 1992
An immune response to human platelet antigens (HPA), as in neonatal alloimmune thrombocytopenia (NAIT) and post-transfusion purpura (PTP), is the exception rather than the rule and evidence is accumulating for the importance of human leucocyte antigen (HLA) class II restriction in this situation.
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An immune response to human platelet antigens (HPA), as in neonatal alloimmune thrombocytopenia (NAIT) and post-transfusion purpura (PTP), is the exception rather than the rule and evidence is accumulating for the importance of human leucocyte antigen (HLA) class II restriction in this situation.
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Platelet aggregation by platelet-clumping substance
Thrombosis Research, 1974Abstract The platelet-clumping substance isolated from rabbit plasma by the authors aggregated washed rabbit platelets, while ADP did not. The presence of AMP or adenosine did not inhibit the appearance of platelet aggregation induced by the clumping substance.
Tadahiro Sano +3 more
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Platelet Glycoproteins in Platelet Aggregation [PDF]
Thrombosis and Haemostasis, 1979 Thrombin stimulation alters the membrane surface of platelets so that specific components on the membrane surface interact. To identify such “aggregation factors”, tne exposed membrane proteins of washed platelets were labeled by lactoperoxidase-catalyzed iodination and tested for their association with cytoskeletal structures.
Lisa K. Jennings +2 more
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