Results 81 to 90 of about 450,650 (277)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
International Journal of CommunicationThis paper analyzes the 2024 Senate hearing on “Big Tech and the Online Child Sexual Exploitation Crisis.” It reveals how misattributions of harm, misaligned solutions, and misdirected remedies proposed may cascade into systemic failures.
Kyooeun Jang
doaj +2 more sources
Evaluating Current Stage of Equity Crowdfunding Adoption in Indonesia: An Exploratory Study
Finance, Accounting and Business AnalysisPurpose: This study investigates the operational processes, oversight practices, investor incentives and business impacts in the localization of equity crowdfunding in Indonesia through an exploratory case study of the LandX platform.
Muhammad Ramadhani Sanjaya +1 more
doaj
The existential stakes of platform governance: a critical literature review. [PDF]
Open Res Eur, 2021 Papaevangelou C.
europepmc +1 more source
Governance of adaptive platform trials
Wellcome Open Research, 2023 Adaptive Clinical Trials (ACT) differ from conventional clinical trials because they permit continual modifications to key components of trial design during the trial. ACTs have grown in prevalence in recent years, with Adaptive Platform Trials (APTs), in particular, having demonstrated their significant scientific, clinical, and public health utility ...
openaire +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
An Analytical study on Navigating Sustainability Challenges and Opportunities in the era of AI and the Gig Economy [PDF]
MATEC Web of ConferencesThe gig economy, characterized by its flexible work arrangements and independent contractors, has witnessed rapid growth in recent years. However, it faces sustainability challenges related to worker welfare, income security, and job classification. This
Nimmagadda Babu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Frontiers in CommunicationDigital platforms and algorithms mediate news production, distribution, and evaluation. This review synthesizes evidence on social media’s influence on news judgment, autonomy, commercialization, public trust, and the amplification of polarization and ...
Hastuti Hastuti +3 more
doaj +1 more source