Results 61 to 70 of about 800,456 (356)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Critical evaluation of potentiometric redox titration in enology [PDF]

open access: yes, 2005
Measurements of the zero current potential of a platinum electrode immersed in solutions of tanins or in wines of various origins, were performed during the additions of a solution of Ti(III), or of a solution of dichlorophenolindophenol (DCPIP), in ...
Comtat, Maurice, Durliat, Hélène
core   +3 more sources

Oxygen reduction reaction on Pt/C at the presence of super paramagnetic of Fe3O4 nanoparticles for PEMFCs [PDF]

open access: yesHydrogen, Fuel Cell & Energy Storage, 2014
In this paper the role of super paramagnetic iron oxide nanoparticles (SPI) on Platinum nanoclusters on activated carbon (Pt/C) for electrocatalytic oxygen reduction reaction was considered.
Mehdi Kheirmand, Freshteh Rastegari-fard
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Microscaled and nanoscaled platinum sensors [PDF]

open access: yes, 2010
We show small and robust platinum resistive heaters and thermometers that are defined by microlithography on silicon substrates. These devices can be used for a wide range of applications, including thermal sensor arrays, programmable thermal sources ...
Chen, Samson   +5 more
core  

Exposure to soluble platinum salts in precious metal refinery workers over a 17-year period [PDF]

open access: hybrid, 2023
Lidwien A.M. Smit   +6 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Platinum thin film anodes for solid acid fuel cells [PDF]

open access: yes, 2011
Hydrogen electro-oxidation kinetics at the Pt | CsH_2PO_4 interface have been evaluated. Thin films of nanocrystalline platinum 7.5–375 nm thick and 1–19 mm in diameter were sputtered atop polycrystalline discs of the proton-conducting electrolyte ...
Haile, Sossina M., Louie, Mary W.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Vapor-deposited platinum as a fuel-cell catalyst [PDF]

open access: yes, 1974
Electrodes are prepared by vacuum deposition of platinum on nickel substrate with conventional vapor-deposition apparatus. Amount of platinum loaded on substrate can be veried by changing exposure time during deposition.
Asher, W. J., Batzold, J. S.
core   +1 more source

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