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Plectin, an unusual target antigen in bullous pemphigoid
British Journal of Dermatology, 2001 Bullous pemphigoid (BP) is a blistering disease associated with autoantibodies directed against two components of hemidesmosomes, BP180 and BP230.To assess whether BP patients have autoantibodies targeting plectin, another hemidesmosomal component showing extensive homology to BP230.Examination of sera from 16 patients with BP, using ...E, Laffitte, B, Favre, L, Fontao, S, Riou, F, Jaunin, K, Tamm, J H, Saurat, L, Borradori +7 moreopenaire +2 more sourcesPlectin-vimentin interaction
2008 Das Cytolinkerprotein Plectin spielt bei der Aufrechterhaltung der Integrität des Zytoskeletts eine entscheidende Rolle, indem es Intermediärfilamente (IFs) mit anderen zytoskelettären Netzwerksystemen verbindet und diese an der Plasmamembran verankert. Weiters dient es als strukturelles Grundgerüst für Signalkaskaden und dürfte ebenfalls eine Funktion openaire +1 more sourcePlectin controls biliary tree architecture and stability in cholestasis
Journal of Hepatology, 2018 Plectin, a highly versatile cytolinker protein, controls intermediate filament cytoarchitecture and cellular stress response. In the present study, we investigate the role of plectin in the liver under basal conditions and in experimental cholestasis.We generated liver-specific plectin knockout (PleΔalb) mice and analyzed them using two cholestatic ...Jiroušková, M. (Markéta), Nepomucká, K. (Kateřina), Oyman-Eyrilmez, G. (Gizem), Kalendová, A. (Alžběta), Havelková, H. (Helena), Sarnová, L. (Lenka), Chalupský, K. (Karel), Schuster, B. (Bjorn), Benada, O. (Oldřich), Mikšátková, P., Kuchař, M., Fabian, O., Sedláček, R. (Radislav), Wiche, G., Gregor, M. (Martin) +14 moreopenaire +4 more sourcesRole of plectin in cytoskeleton organization and dynamics
Journal of Cell Science, 1998 ABSTRACT Plectin and its isoforms are versatile cytoskeletal linker proteins of very large size (>500 kDa) that are abundantly expressed in a wide variety of mammalian tissues and cell types. Earlier studies indicated that plectin molecules were associated with and/or directly bound to subcomponents of all three major cytoskeletal openaire +3 more sourcesPlectin Autosomal Recessive
2009 Markus Braun-Falco, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, Richard Lorenz, Guido Adler, David C. Whitcomb, Dhiraj Yadav, Johannes Bode, Martin Wabitsch, Klaus-Michael Debatin, Pamela Fischer Posovzsky, Akmal Hassan, Mosaad Megahed, Tord M. Lundgren, Markus Pfister, Hans-Peter Zenner, Rossana Berardi, Chiara Pierantoni, Mario Scartozzi, Stefano Cascinu, Geoffrey N. Hendy, Johannes Schwarz, Alexander Storch, John-John B. Schnog, Victor E. A. Gerdes, Susanne A. Schneider, Kailash P. Bhatia, Adriana C. Gittenberger-de Groot, Regina Bökenkamp, Marco C. DeRuiter, Alexander K. C. Leung, Andrew L. Wong, Undine E. Lang, Alexander K. C. Leung, Alexander K. C. Leung, Muammer Seyhan, Silke Hofmann, Leena Bruckner-Tuderman, Silke Hofmann, Leena Bruckner-Tuderman, Silke Hofmann, Leena Bruckner-Tuderman, Peter Kopp, Douglas Forrest, Emine Dibek Misirlioğlu, Nursel Alpan, Mark Oette, Massimo Imazio, Kavitha M. Chinnaiyan, Laxmi S. Mehta, Mushtaq A. Bhat, Javeed I. Bhat, Gerald Stöber, André Reis, Jan Rémi, Soheyl Noachtar, Karin Jurkat-Rott, Frank Lehmann-Horn, Marinella Holzhausen, Nathalie Vergnolle, Martin Schillinger, Hans-Jürgen Gdynia, Albert C. Ludolph, Thomas Namdar, Claus Ferdinand Eisenberger, Wolfram Trudo Knoefel, Pere Ginés, Mónica Guevara, Antonio L. Cuesta-Muñoz, Henk Eijer, Markus Böhm, Thomas A. Luger, Flemming Güttler, Per Guldberg, Richard Koch, Kathryn Moseley, Graeme Eisenhofer, Karel Pacak, James V. Leonard, Jaak Jaeken, Michael A. Becker, Ulrich Stephani, Kendall S. Frazier, Markus Böhm, Thomas A. Luger, Alexander K. C. Leung, Reginald S. Sauve, Verena Matejas, Martin Zenker, Alexander K. C. Leung, Alexander K. C. Leung, William Lane M. Robson, Stefan Beissert, Alexander K. C. Leung, William Lane M. Robson, Tom Y. Woo, Alexander K. C. Leung, Hugo Ten Cate, Richard W. Light, Patricia T. Bozza, Jorge I. Salluh, Michael A. Jantz, Sergio L. Vargas, Rade Tomic, Jesse Roman, Abdullah F. Mobeireek, Mohammad Khalid, Harrys A. Torres, Roy F. Chemaly, Rade Tomic, Jesse Roman, Richard W. Light, Angela Dispenzieri, Sabine Krause, Hanns Lochmüller, Julia Weihrauch, Thomas Krieg, Wolfgang Kühn, Gerd Walz, Georg H. Merker, Ralf Kubitz, Dieter Häussinger, John-John B. Schnog, Victor E. A. Gerdes, Giovanna Musco, Guido Stoll, Klaus V. Toyka, Alexander K. C. Leung, Alexander K. C. Leung, William Lane M. Robson, Markus Böhm, Thomas A. Luger, Elena Pischik, Raili Kauppinen, Jorge Frank, Thomas Schwarz, Manish Thapar, Herbert. L. Bonkovsky, Jeffrey C. Wagner, A. Gordon Smith, Maria Mela, Ulrich Thalheimer, Dimitrios Samonakis, Andrew K. Burroughs, Maria Mela, Ulrich Thalheimer, Dimitrios Samonakis, Andrew K. Burroughs, Yogesh M. Shastri, Jürgen M. Stein, Ronnen H. Segman, Arieh Y. Shalev, Giris Jacob, David Robertson, Alexander K. C. Leung, William Lane M. Robson, Alexander K. C. Leung, Katja Lampinen, Karolina Kublickiene, Risto Kaaja, Radosław Lenarczyk, Oskar Kowalski, Zbigniew Kalarus, Dan Wichterle, Alexander K. C. Leung, Jamie Maguire, Istvan Mody, Katrien Janssens, Filip Vanhoenacker, Wim Van Hul, Hans-Jürgen Gdynia, Albert C. Ludolph, James V. Leonard, Hugo Ten Cate, Karel Geboes, Gert Van Assche, Hugo Ten Cate, Jo H. M. Berden, Toin H. Van Kuppevelt, Angelique L. Rops, Hugo Ten Cate, Hugo Ten Cate, Jorge Frank, Thomas Schwarz, Christina M. Ambros-Rudolph, Valéria Lamounier-Zepter, Christie P. Thomas, Christie P. Thomas, Christie P. Thomas, Christian A. Koch, Lee S. Weinstein, Caroline Silve, Alexander K. C. Leung, Jouni Uitto, Qiujie Jiang, Alexander K. C. Leung +199 moreopenaire +1 more sourcePlectin Mutations in Progressive Familial Intrahepatic Cholestasis
Hepatology, 2019 Shang-Hsin, Wu, Jacob Shujui, Hsu, Hui-Ling, Chen, Mu-Ming, Chien, Jia-Feng, Wu, Yen-Hsuan, Ni, Bang-Yu, Liou, Ming-Chih, Ho, Yung-Ming, Jeng, Mei-Hwei, Chang, Pei-Lung, Chen, Huey-Ling, Chen +11 moreopenaire +2 more sources