Results 11 to 20 of about 29,620 (204)

Massive Plexiform Neurofibroma of the Neck and Larynx

International Archives of Otorhinolaryngology, 2015
Introduction Laryngeal neurofibromas are extremely rare, accounting for only 0.03 to 0.1% of benign tumors of the larynx. Objectives To report the first case of massive neck plexiform neurofibroma with intralaryngeal (supraglottic) extension
Mohammad Waheed El-Anwar
exaly   +3 more sources

Revisiting the NPcis mouse model: A new tool to model plexiform neurofibroma. [PDF]

PLoS ONE
Neurofibromatosis Type I (NF1) is a rare genetic disorder. NF1 patients frequently develop a benign tumor in peripheral nerve plexuses called plexiform neurofibroma.
Camille Plante, Teddy Mohamad, Dhanushka Hewa Bostanthirige, Michel Renaud, Harsimran Sidhu, Michel ElChoueiry, Jean-Paul Sabo Vatasescu, Mikael Poirier, Sameh Geha, Jean-Philippe Brosseau   +9 more
doaj   +2 more sources

Plexiform neurofibroma

Radiopaedia.org, 2021
Irvine Sihlahla
semanticscholar   +6 more sources

Plexiform neurofibroma

Cleveland Clinic Journal of Medicine, 2016
Plexiform neurofibromas represent an uncommon variant (30%) of neurofibromatosis type 1 (NF-1) in which neurofibromas arise from multiple nerves as bulging and deforming masses involving also connective tissue and skin folds.We report a rare case of a 30-year-old man who presented with a progressive facial deformity that began in early childhood.
Tchernev, Georgi, Chokoeva, Anastasiya Atanasova, Patterson, James W., Bakardzhiev, Ilko, Wollina, Uwe, Tana, Claudio   +5 more
  +7 more sources

Oral plexiform neurofibroma

Journal of Dental Sciences, 2016
Yu-Hsueh Wu
doaj   +3 more sources

Plexiform neurofibroma [PDF]

Radiopaedia.org, 2020
Dai Roberts, F. Salahshour
semanticscholar   +3 more sources

A case report of a 4-year-old girl with neurofibromatosis type 1

Cancer Treatment and Research Communications, 2022
Neurofibromatosis type 1 is a rare genetic disorder, which is a benign nerve tumor resulting from aberrant growth of the cells of nerve sheath. NF1 patients were associated with multisystem involvement, characterized by neurofibroma, of which 50% were ...
Mengying Peng, Yuqing Zhang, Qiong Zhou
doaj   +1 more source

Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma

Clinical Cancer Research, 2023
Purpose: Plexiform neurofibromas (PNF) are peripheral nerve sheath tumors that cause significant morbidity in persons with neurofibromatosis type 1 (NF1), yet treatment options remain limited.
Alyssa C Flint, Dana K. Mitchell, Steve Angus, A. Smith, Waylan K Bessler, Li Jiang, H. Mang, Xiaohong Li, Qingbo Lu, B. Rodriguez, G. Sandusky, A. Masters, Chi Zhang, P. Dang, Jenna K. Koenig, Gary L. Johnson, W. Shen, Jiangang Liu, A. Aggarwal, Gregory P. Donoho, Melinda D Willard, S. Bhagwat, D. Clapp, Steven D. Rhodes   +23 more
semanticscholar   +1 more source

Combining SOS1 and MEK Inhibitors in a Murine Model of Plexiform Neurofibroma Results in Tumor Shrinkage

Journal of Pharmacology and Experimental Therapeutics, 2023
Individuals with neurofibromatosis type 1 develop rat sarcoma virus (RAS)–mitogen-activated protein kinase–mitogen-activated and extracellular signal-regulated kinase (RAS-MAPK-MEK)–driven nerve tumors called neurofibromas.
Mark Jackson, Niousha Ahmari, Jianqiang Wu, Tilat A Rizvi, E. Fugate, Mi-Ok Kim, E. Dombi, Heribert Arnhof, G. Boehmelt, M. Düchs, Clive J Long, U. Maier, F. Trapani, M. H. Hofmann, N. Ratner   +14 more
semanticscholar   +1 more source

Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment

JCI Insight, 2022
To define alterations early in tumor formation, we studied nerve tumors in neurofibromatosis 1 (NF1), a tumor predisposition syndrome. Affected individuals develop neurofibromas, benign tumors driven by NF1 loss in Schwann cells (SCs).
Leah J. Kershner, Kwangmin Choi, Jianqiang Wu, Xiyuan Zhang, Melissa R. Perrino, N. Salomonis, J. Shern, N. Ratner   +7 more
semanticscholar   +1 more source