Results 131 to 140 of about 6,579 (168)

Corticospinal Tract Development, Evolution, and Skilled Movements. [PDF]

Mov Disord
Roze E, Dubacq C, Welniarz Q.
europepmc   +1 more source

The Etiology of Moebius Syndrome-Making the Case for Animal Models. [PDF]

Int J Mol Sci
Tracicaru MP, Tracicaru RV, Hînganu D, Hînganu MV.   +3 more
europepmc   +1 more source

Knockdown of Plexin C1 induces epithelial-to-mesenchymal transition and confers resistance to multikinase inhibitors in hepatocellular carcinoma cells. [PDF]

Turk J Biol
Topcu GG, Aysan A, Dik Ş, Şeker M, Bahçekapili MB, Topkaraoğlu S, Yavuzer D, Yağci T.   +7 more
europepmc   +1 more source

EGFR ligand Angiogenin predicts response to ALK5 inhibition in pancreatic cancer via a TNF-α paracrine axis in tumor-associated macrophages. [PDF]

Oncogene
Pietrobono S, De Vita V, Mangiameli D, Aparo A, Lorenzo ES, Bonato A, Bertolini M, Scarlato E, Casalino S, Quinzii A, Zecchetto C, Melisi D.   +11 more
europepmc   +1 more source

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Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains

Biochemical and Biophysical Research Communications, 2003
Semaphorin 3A (Sema3A) is a member of semaphorins and functions as an axonal repulsive guidance molecule. Neuropilin-1 and plexin-As form receptor complexes for Sema3A and plexin-As are thought to initiate the intracellular signaling cascade. However, the molecule by which plexin-As transduce their signal is not well understood.
Hiroshi, Usui, Masahiko, Taniguchi, Takehiko, Yokomizo, Takao, Shimizu   +3 more
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Semaphorins and plexins as therapeutic targets

Nature Reviews Drug Discovery, 2014
Semaphorins are membrane-bound or diffusible factors that regulate key cellular functions and are involved in cell-cell communication. Most of the effects of semaphorins are mediated by plexins. Work over the past decade has revealed crucial functions of the semaphorin-plexin system in mammalian physiology. It has also become clear that semaphorins and
Thomas, Worzfeld, Stefan, Offermanns
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Plexins are partners for neuropilins

Science Signaling, 1999
Membrane-bound and secreted semaphorins regulate a number of cell adhesion processes including axon guidance in the nervous system. However, little is known about the receptors to which they bind. Although neuropilins bind to secreted class 3 semaphorins (Sema3), it is thought that a coreceptor might be required to transduce Sema3 signals
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Plexins: axon guidance and signal transduction

Cellular and Molecular Life Sciences, 2005
Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as semaphorins, ephrins and netrin. Plexins function as receptors for the repulsive axonal guidance molecules semaphorins.
M, Negishi, I, Oinuma, H, Katoh
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The expression of plexins during mouse embryogenesis

Gene Expression Patterns, 2005
Plexins are large transmembrane proteins that are receptors for semaphorins, either alone or in a complex with neuropilin-1 or -2. Nine different mouse plexins have been found: Plexin-A1-4, -B1-3, -C1 and -D1. The expression and function of plexins in non-neuronal tissues has been poorly characterized, although Plexin-A1 has been shown to have a role ...
Nina M, Perälä, Tiina, Immonen, Hannu, Sariola   +2 more
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Identification of Plexin Family Molecules in Mice

Biochemical and Biophysical Research Communications, 1996
By screening of E17.5 mouse brain cDNA libraries, we isolated two cDNAs encoding new plexin-like proteins. Sequencing revealed that these two proteins were type 1 membrane proteins which showed over 60% identity at the amino acid level to mouse plexin 1.
T, Kameyama, Y, Murakami, F, Suto, A, Kawakami, S, Takagi, T, Hirata, H, Fujisawa   +6 more
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