Results 1 to 10 of about 14,042 (117)
Inflammatory Semaphorins in the Pathogenesis and Prognosis of Acute Ischemic Stroke [PDF]
MedicinaBackground and Objectives: Semaphorins are immunoregulatory proteins involved in inflammation and neurovascular modulation. Their roles in ischemic stroke pathogenesis and prognosis have recently gained attention.
Esen Çiçekli +2 more
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The Relationship Between Immune Semaphorins and Myasthenia Gravis [PDF]
Brain and BehaviorObjective Myasthenia gravis (MG) is an autoimmune disease involving several immune mechanisms. Recently, semaphorins have emerged as potential diagnostic and prognostic biomarkers in autoimmune neurological and non‐neurological diseases.
Dilcan Kotan +2 more
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SEMA3B is associated with disease activity and infliximab response in IBD patients but does not contribute to the development of intestinal inflammation in vivo [PDF]
Frontiers in ImmunologyBackgroundInflammatory bowel disease (IBD) is a chronic inflammatory disorder with increasing worldwide incidence and prevalence. While current treatment options alleviate part of the socioeconomic burden of this disease, new biomarkers and safer ...
Laura Arosa +6 more
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Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation. [PDF]
PLoS ONE, 2017 Semaphorin-7A is a glycosylphosphatidylinositol-anchored protein, initially characterized as an axon guidance protein. Semaphorin-7A also contributes to immune cell regulation and may be an essential pro-fibrotic factor when expressed by non-fibroblast ...
Stephane Esnault +6 more
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Semaphorin 6A improves functional recovery in conjunction with motor training after cerebral ischemia. [PDF]
PLoS ONE, 2010 BACKGROUND: We have previously identified Semaphorin 6a (Sema6A) as an upregulated gene product in a gene expression screen in cortical ischemia [1]. Semaphorin 6a was regulated during the recovery phase following ischemia in the cortex. Semaphorin 6a is
Andreas Rogalewski +8 more
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Cell Death and Disease, 2022 Abnormal activation of synovial fibroblasts (SFs) plays an important role in rheumatoid arthritis (RA), the mechanism of which remains unknown. The purpose of our study is to comprehensively and systematically explore the mechanism for Semaphorin 5A ...
Qi Cheng +8 more
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Frontiers in Cell and Developmental Biology, 2023 The ovarian follicle is a complex structure that protects and helps in the maturation of the oocyte, and then releases it through the controlled molecular and structural remodeling process of ovulation.
Alaknanda Emery +5 more
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Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury. [PDF]
PLoS ONE, 2013 Semaphorin 3A is a secreted protein that regulates cell motility and attachment in axon guidance, vascular growth, immune cell regulation and tumor progression. However, nothing is known about its role in kidney pathophysiology.
Calpurnia Jayakumar +5 more
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MICAL-mediated oxidation of actin and its effects on cytoskeletal and cellular dynamics
Frontiers in Cell and Developmental Biology, 2023 Actin and its dynamic structural remodelings are involved in multiple cellular functions, including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle contraction.
Sudeepa Rajan +3 more
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Technology in Cancer Research & Treatment, 2020 Background: Esophageal squamous cell carcinoma is one of the leading aggressive malignancies with high mortality. Semaphorin 3F has been reported to be involved in lymphangiogenesis by interacting the vascular endothelial growth factor C/neuropilin 2 ...
Zhen Xie MD +5 more
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