Results 1 to 10 of about 89,492 (311)

Syntehsis and evaluation of Gd3+ -Trp-PLGA as novel nanosized MR tumor imaging candidate [PDF]

open access: yesNanomedicine Journal, 2021
Objective(s): Early detection of cancer can significantly increase the likelihood of successful treatment, and imaging assay can have a significant impact on cancer diagnosis.
Elnaz Salehian   +8 more
doaj   +1 more source

Recent progress in the intranasal PLGA-based drug delivery for neurodegenerative diseases treatment [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
One of the most challenging problems of the current treatments of neurodegenerative diseases is related to the permeation and access of most therapeutic agents to the central nervous system (CNS), prevented by the blood-brain barrier (BBB).
Nasim Aghaei Delche   +6 more
doaj   +1 more source

Hyperthermia Efficacy of PEGylated-PLGA Coated Monodisperse Iron Oxide Nanoparticles

open access: yesHittite Journal of Science and Engineering, 2023
Magnetic nano hyperthermia (MNH) is a promising technique for the treatment of a variety of malignancies. This non-invasive technique employs magnetic nanoparticles and alternating magnetic fields to generate local heat at the tumor location, which ...
Fatih Senturk
doaj   +1 more source

Protective Potential of Conjugated P. aeruginosa LPS –PLGA Nanoparticles in Mice as a Nanovaccine [PDF]

open access: yesIranian Journal of Immunology, 2020
Background: Pseudomonas aeruginosa has an important role in nosocomial infections. Objective: To evaluate biological activity of the detoxified LPS (D-LPS) entrapped into Poly lactic-co-glycolic acid (PLGA) nanoparticles. Materials: LPS was extracted and
Leila Safari Zanjani   +4 more
doaj   +1 more source

DEVELOPMENT AND CHARACTERISATION OF POLYPROPYLENE- PLGA ELECTROSPUN HERNIA MESHES [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2022
The use of polymer hernia meshes lead to significant reduction in the rate of relapse, pain minimisation, overall improving the post-operative outcomes of abdominal hernia.
GRADISTEANU PIRCALABIORU Gratiela   +4 more
doaj  

Single administration vaccines: delivery challenges, in vivo performance, and translational considerations

open access: yesExpert Review of Vaccines, 2023
Introduction With a limited global supply of vaccines and an increasing vaccine hesitancy, improving vaccination coverage has become a priority. Current vaccination regimes require multiple doses to be administered in a defined schedule where missed ...
Kyprianos Michaelides   +7 more
doaj   +1 more source

Tendon Biomimetic Electrospun PLGA Fleeces Induce an Early Epithelial-Mesenchymal Transition and Tenogenic Differentiation on Amniotic Epithelial Stem Cells

open access: yesCells, 2020
Background. The design of tendon biomimetic electrospun fleece with Amniotic Epithelial Stem Cells (AECs) that have shown a high tenogenic attitude may represent an alternative strategy to overcome the unsatisfactory results of conventional treatments in
Valentina Russo   +14 more
doaj   +1 more source

Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy

open access: yesDrug Delivery, 2022
The traditional systemic chemotherapy through intravenous infusion of doxorubicin (DOX) has many side effects. The aim of this study was to develop a PLGA-based DOX-loaded implant and to evaluate the efficacy and drug metabolism distribution of the ...
Peng He   +8 more
doaj   +1 more source

mpact of molecular weight of polyethylene glycol on physicochemical characteristics of polymeric nanoparticles encapsulating pimozide

open access: yesBritish Journal of Pharmacy, 2023
The aim of the study is to examine the effect of the molecular weight of Polyethylene glycol (PEG) on the properties of nanoparticles. PEGlyation of nanoparticles is a promising approach to extend the circulation time and protect nanoparticles from
HardipSinh Barad   +2 more
doaj   +1 more source

Branched PLGA derivatives with tailored drug delivery properties

open access: yesActa Pharmaceutica, 2020
Despite several shortcomings such as extreme hydrophobicity, low drug capacity, characteristic triphasic drug release pattern with a high burst effect, poly(lactic-co-glycolic acid derivatives are widely used in drug delivery.
Snejdrova Eva   +4 more
doaj   +1 more source

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