Results 41 to 50 of about 89,492 (311)
Vaccines, 2022 Taxanes, microtubule stabilizing agents, are extensively used in the treatment of non-small cell lung cancer (NSCLC). However, their clinical effectiveness remains restricted owing to significant adverse effects and drug resistance.
Parul Gupta +6 more
doaj +1 more source
3D multi-agent models for protein release from PLGA spherical particles with complex inner morphologies [PDF]
, 2008 In order to better understand and predict the release of proteins from bioerodible micro- or nanospheres, it is important to know the influences of different initial factors on the release mechanisms.
A Göpferich +22 more
core +1 more source
Recent advances in 3D printing of biomaterials. [PDF]
, 2015 3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of ...
Chia, Helena N, Wu, Benjamin M
core +2 more sources
Surface modification of PLGA microspheres [PDF]
Journal of Biomedical Materials Research Part A, 2003 AbstractMicrospheres made of poly(lactic‐co‐glycolic acid) (PLGA) are biocompatible and biodegradable, rendering them a promising tool in the context of drug delivery. However, nonspecific adsorption of plasma proteins on PLGA micro‐ and nanospheres is a main limitation of drug targeting.
M, Müller +7 more
openaire +2 more sources
A nanoparticle loaded nasal sol-gel system of midazolam hydrochloride for the management of intermittent seizures [PDF]
Nanomedicine JournalObjective(s): Midazolam hydrochloride is a short-acting hypnotic sedative with anticonvulsant properties. Considering the poor bioavailability, rapid elimination, and inconvenience of administering oral medication in epileptic conditions, this study ...
Venkatesh Srinivasan +3 more
doaj +1 more source
Influence of electrostatic interactions in electrophoretic membrane contactors [PDF]
, 2002 In electrophoretic separators, a porous membrane is used to put into contact two flowing liquids between which an electrically driven mass transfer takes place. As far as charged solutes are concerned, the mass transfer can be affected by electrostatic
Galier, Sylvain +1 more
core +2 more sources
Enhanced Osteogenesis of Adipose-Derived Stem Cells by Regulating Bone Morphogenetic Protein Signaling Antagonists and Agonists. [PDF]
, 2016 UnlabelledAlthough adipose-derived stem cells (ASCs) are an attractive cell source for bone tissue engineering, direct use of ASCs alone has had limited success in the treatment of large bone defects.
Aghaloo, Tara L +11 more
core +2 more sources
Formulation of stabilizer-free, nontoxic PLGA and elastin-PLGA nanoparticle delivery systems
International Journal of Pharmaceutics, 2021 Biocompatible nanoparticles composed of poly(lactic-co-glycolic acid) (PLGA) are used as drug and vaccine delivery systems because of their tunability in size and sustained release of cargo molecules. While the use of toxic stabilizers such as polyvinyl alcohol (PVA) limit the utility of PLGA, stabilizer-free PLGA nanoparticles are rarely used because ...
Zachary R, Stromberg +11 more
openaire +2 more sources
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Majalah Obat Tradisional, 2022 Pegagan is a plant that plays an important role in health because of its secondary metabolite. However, many secondary metabolites tend to be unstable when exposed to UV light and oxygen such as flavonoid and terpenoid.
Elsa Fitria Apriani +2 more
doaj +1 more source