Results 101 to 110 of about 115,209 (391)

Gender and ploidy in cancer survival [PDF]

Cellular Oncology, 2011
Females carry a better prognosis than men for many cancer types. We hypothesized that chromosomal changes, in particular numerical alterations of the sex chromosomes or the presence of near-triploidy may contribute to these gender differences.To characterize the influence of gender a literature search was performed for survival data of 27 tumor types ...
Schulze, Susanne, Petersen, Iver
openaire   +2 more sources

Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross‐Species Multi‐Cohort Bioinformatic Study

Head &Neck, EarlyView.
ABSTRACT Background The loss of the Y chromosome (LOY) and the extreme down‐regulation of Y chromosome gene expression (EDY) are frequently observed in oral squamous cell carcinoma (OSCC). However, their roles in oral potentially malignant disorders (OPMDs) are unclear.
Rui Han, Jos B. Poell, Cristina Conde‐Lopez, Tuula Salo, Ina Kurth, Ruud H. Brakenhoff, Jochen Hess   +6 more
wiley   +1 more source

Molecular footprints of the Holocene retreat of dwarf birch in Britain [PDF]

, 2014
© 2014 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original ...
Atkinson MD, Avise JC, Brown IR, Brown IR, Furrer R, Hammer Ø, Huntley B, Linnaeus C, Mellersh C, Phillips SJ, Pritchard JK, R Core Team, Rich TCG, Stace CA, Stebbins GL   +14 more
core   +1 more source

Three-dimensional direct measurement of cardiomyocyte volume, nuclearity, and ploidy in thick histological sections

Scientific Reports, 2016
Quantitative assessment of myocardial development and disease requires accurate measurement of cardiomyocyte volume, nuclearity (nuclei per cell), and ploidy (genome copies per cell).
J. Bensley, R. De Matteo, R. Harding, M. Black   +3 more
semanticscholar   +1 more source

Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella Review

Head &Neck, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) represents the most common oral potentially malignant disorder globally, with highly variable reported malignant transformation (MT) rates creating challenges for evidence‐based clinical management. Objective To systematically synthesize evidence on MT prevalence in OL and evaluate potential predictive ...
Mohammed Taib Fatih, Mohammed Khalid Mahmood, Balkees Taha Garib, Yad Mariwan Mohammed Amin, Ranjdar Mahmood Talabani, Tara Ali Rasheed, Handren Ameer Kurda, Balen Hamid Qadir, Zana Fuad Noori, Mohammed Aso Abdulghafor, Ariwan Othman Saeed, Herve Tassery, Delphine Tardivo, Romain Lan   +13 more
wiley   +1 more source

Interspecific somatic hybrids between Solanum bulbocastanum and S. tuberosum and their haploidization for potato breeding. [PDF]

, 2012
Protoplast fusion between incongruent Solanum bulbocastanum and S. tuberosum haploids was accomplished to produce hybrids combining elite traits from both parents. We identified 11 somatic hybrids out of 42 regenerants analyzed through ISSR markers. Some
AVERSANO, RICCARDO, Cardi T., CARPUTO, DOMENICO, CARUSO, IMMACOLATA, DI MATTEO, ANTONIO, FRUSCIANTE, LUIGI, IOVENE, MARINA, Savarese S.   +7 more
core   +2 more sources

Widespread co-occurrence of multiple ploidy levels in fragile ferns (Cystopteris fragilis complex; Cystopteridaceae) probably stems from similar ecology of cytotypes, their efficient dispersal and inter-ploidy hybridization.

Annals of Botany, 2018
BACKGROUND AND AIMS Polyploidy has played an important role in the evolution of ferns. However, the dearth of data on cytotype diversity, cytotype distribution patterns and ecology in ferns is striking in comparison with angiosperms and prevents an ...
K. Hanušová, Martin Čertner, Tomáš Urfus, P. Koutecký, J. Košnar, C. Rothfels, V. Jarolímová, J. Ptáček, Libor Ekrt   +8 more
semanticscholar   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Haploidy-linked cell proliferation defects limit larval growth in zebrafish

Open Biology
Haploid larvae in non-mammalian vertebrates are lethal, with characteristic organ growth retardation collectively called ‘haploid syndrome’. In contrast to mammals, whose haploid intolerance is attributed to imprinting misregulation, the cellular ...
Kan Yaguchi, Daiki Saito, Triveni Menon, Akira Matsura, Miyu Hosono, Takeomi Mizutani, Tomoya Kotani, Sreelaja Nair, Ryota Uehara   +8 more
doaj   +1 more source

PLOIDY AND GENE EXPRESSION IN CLEMENTINE

Acta Horticulturae, 2015
Polyploidy has long been recognized as an important force in the evolution of flowering plants and often results in novel phenotypes having advantages in adaptation and major interest for agriculture. Many crops, including citrus, are bred to a higher level of ploidy in search of desirable traits.
Niñoles Rodenes, Regina, Aleza, Pablo, Castillo, Mª Cruz, Navarro Lucas, Luis, Ancillo, Gema   +4 more
openaire   +3 more sources