Results 41 to 50 of about 100,488 (302)
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The evolution of new metabolic pathways has been a driver of diversification from the last universal common ancestor 3.8 billion y ago to the present.
Juhan Kim +11 more
semanticscholar +1 more source
Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Retraction]
Clinical Pharmacology: Advances and Applications, 2021 Hinz M, Stein A, Cole T. Clin Pharmacol. 2014;6:189–194.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This perspective article cites several original ...
Hinz M, Stein A, Cole T
doaj
Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO) [PDF]
, 2017 PNPO deficiency is responsible of severe neonatal encephalopathy, responsive to pyridoxal-5’-phosphate (PLP) or pyridoxine. Recent studies widened the phenotype of this condition and detected new genetic variants on PNPO gene, whose pathogenetic role and
Carducci, Carla +11 more
core +2 more sources
Well-posedness analysis of multicomponent incompressible flow models [PDF]
, 2020 In this paper, we extend our study of mass transport in multicomponent isothermal fluids to the incompressible case. For a mixture, incompressibility is defined as the independence of average volume on pressure, and a weighted sum of the partial mass ...
Bothe, Dieter, Druet, Pierre-Etienne
core +4 more sources
The FEBS Journal, 2019 Cysteine desulfurase enzymes catalyze sulfur mobilization from l‐cysteine to sulfur‐containing biomolecules such as iron‐sulfur (Fe‐S) clusters and thio‐tRNAs.
R. Nakamura +4 more
semanticscholar +1 more source
On the convergence of adaptive nonconforming finite element methods for a class of convex variational problems [PDF]
, 2011 We formulate and analyze an adaptive nonconforming finite element method for the solution of convex variational problems. The class of minimization problems we admit includes highly singular problems for which no Euler–Lagrange equation (or inequality ...
Ortner, Christoph, Praetorius, Dirk
core +2 more sources
Journal of General and Applied Microbiology, 2018 The gene ybhA of Escherichia coli encodes a phosphatase that has an in vitro specificity to dephosphorylate pyridoxal 5'-phosphate (PLP or vitamin B6), a co-factor for aminotransferases and other enzymes. In this study, we found that excess pyridoxal (PL)
Ryota Sugimoto +3 more
semanticscholar +1 more source
Role of Proteolipid Protein in HSV-1 Entry in Oligodendrocytic Cells. [PDF]
PLoS ONE, 2016 Herpes simplex virus type 1 (HSV-1) has the ability to enter many different hosts and cell types by several strategies. This highly prevalent alphaherpesvirus can enter target cells using different receptors and different pathways: fusion at a neutral pH,
Raquel Bello-Morales +9 more
doaj +1 more source
Structural and biophysical analysis of important biomedical enzymes and nano-architectures [PDF]
, 2008 Dopa decarboxylase (DDC) is an important enzyme in the catecholamine biosynthesis pathways. Catecholamines, e.g., dopamine, serotonin, etc. often are the major neuromodulators or neurotransmitters.
Chattopadhyay, Arundhati
core +1 more source
Facile immobilization of pyridoxal 5′-phosphate using p-diazobenzoyl-derivatized Sepharose 4B
Results in Chemistry, 2023 Pyridoxal 5′-phosphate (PLP) is a ubiquitous and versatile cofactor utilized by numerous enzymes involved in amino acid biosynthetic pathways. Immobilized PLP is a valuable tool to isolate unknown PLP-dependent enzymes in nature or to perform in vitro ...
Kun-Hwa Lee +2 more
doaj +1 more source