Results 71 to 80 of about 184,232 (306)
100 ways to make a Japanese house [PDF]
, 2012 In lieu of an abstract, here is a brief excerpt of the content: Scenes of children making dollhouses are something of a leitmotif in Rumer Godden’s celebrated doll stories.
Field, Hannah
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
mSphere, 2018 The pathogenesis of foot-and-mouth disease virus (FMDV) in cattle was investigated through early and late stages of infection by use of an optimized experimental model for controlled contact exposure. Time-limited exposure of cattle to FMDV-infected pigs
Carolina Stenfeldt +8 more
doaj +1 more source
Pathogens, 2020 Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish +4 more
doaj +1 more source
A computer-assisted existence proof for Emden's equation on an unbounded L-shaped domain
, 2016 We prove existence, non-degeneracy, and exponential decay at infinity of a non-trivial solution to Emden's equation $-\Delta u = | u |^3$ on an unbounded $L$-shaped domain, subject to Dirichlet boundary conditions. Besides the direct value of this result,
Pacella, Filomena +2 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Proceedings of the 3rd conference on Message understanding - MUC3 '91, 1991 Perhaps the most important facts about our participation in MUC-3 reflect our starting point and goals. In March, 1990, we initiated a pilot study on the feasibility and impact of applying statistical algorithms in natural language processing. The experiments were concluded in March, 1991 and lead us to believe that statistical approaches can ...
Ralph Weischedel +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source