Results 91 to 100 of about 258,225 (234)
Legislation governing pluripotent stem cells in South Africa
One of the most exciting areas of medical research involves the use of stem cells for the treatment of patients with a variety of diseases and for tissue repair.
Michael Pepper, C Gouveia, M Slabbert
doaj +1 more source
THRB is a nuclear receptor, regulating gene expression dependent on thyroid hormone (TH) binding. The same receptor mediates signaling pathway activation in the cytosol.
Katarzyna A. Ludwik+4 more
doaj
The transcriptome of human pluripotent stem cells
Human Embryonic Stem Cells (hESCs) are in vitro derivatives of the inner cell mass of the blastocyst and are characterized by an undifferentiated and pluripotent state that can be perpetuated in time, indefinitely. hESCs provide a unique opportunity to both dissect the molecular mechanisms that are predisposed to the maintenance of pluripotency and ...
Kin Fai Au, Vittorio Sebastiano
openaire +3 more sources
Allan-Herndon-Dudley syndrome (AHDS) is an X-linked disorder characterized by profound psychomotor impairment. It is caused by mutations in the SLC16A2 gene, which encodes monocarboxylate transporter 8 (MCT8), a crucial thyroid hormone transporter.
Katarzyna A. Ludwik+5 more
doaj
Induced pluripotent stem cells: advances to applications
Timothy J Nelson1, Almudena Martinez-Fernandez1, Satsuki Yamada1, Yasuhiro Ikeda2, Carmen Perez-Terzic1, Andre Terzic11Marriott Heart Disease Research Program, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA; 2Department of ...
Timothy J Nelson+3 more
doaj
Editorial: The pathogenesis of aplastic anemia: a defective pluripotent hematopoietic stem cell with inappropriate balance of differentiation and self-replication [PDF]
DR Boggs, S. S. Boggs
openalex +1 more source
Background: In regenerative medicine, use of each of the mesenchymal stem cells derived from bone marrow, cord blood, and adipose tissue, has several cons and pros.
T Foroutan+4 more
doaj
Isolation of murine pluripotent hemopoietic stem cells. [PDF]
Jan Visser+4 more
openalex +1 more source
The reader will immediately get the feeling, from the preface of the book, of handling a laboratory manual where no one needed information is missing: the preface itself is a chapter dealing with the historical reconstruction of the paradigmatic breakthroughts occurred in the last few decades in the stem cell world. I appreciated so much this aspect, a
openaire +3 more sources
Bcl-2-associated X protein (BAX) and Blc-2 homologous antagonist killer 1 (BAK) are two pro-apoptotic members of BCL2 family. Here, two BAX/BAK double knock-out human induced pluripotent stem cell lines (iPSC) we generated using CRISPR-Cas9 to generate ...
Katarzyna Anna Ludwik+6 more
doaj