Results 131 to 140 of about 980,977 (401)

Legislation governing pluripotent stem cells in South Africa

South African Journal of Bioethics and Law, 2015
One of the most exciting areas of medical research involves the use of stem cells for the treatment of patients with a variety of diseases and for tissue repair.
Michael Pepper, C Gouveia, M Slabbert
doaj   +1 more source

Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts [PDF]

, 2012
Katrin Streckfuß‐Bömeke, Frieder Wolf, Azadeh Azizian, Michael Stauske, Malte Tiburcy, Stefan Wagner, Daniela Hübscher, Ralf Dressel, Simin Chen, Jörg Jende, Gerald Wulf, Verena Lorenz, Michael P. Schön, Lars S. Maier, Wolfram H. Zimmermann, Gerd Hasenfuß, Kaomei Guan   +16 more
openalex   +1 more source

Endothelial cells derived from patients' induced pluripotent stem cells for sustained factor VIII delivery and the treatment of hemophilia A. [PDF]

, 2020
Hemophilia A (HA) is a bleeding disorder characterized by spontaneous and prolonged hemorrhage. The disease is caused by mutations in the coagulation factor 8 gene (F8) leading to factor VIII (FVIII) deficiency.
Agu, Emmanuel, Conroy, Kelsey, Cortez-Toledo, Elizabeth, Gao, Kewa, Hyllen, Alicia A, Nolta, Jan A, Pan, Guangjin, Rose, Melanie, Wang, Aijun, Zhou, Ping   +9 more
core   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells [PDF]

, 2015
Young Gie Chung, Shogo Matoba, Yuting Liu, Jin Hee Eum, Falong Lu, Wei Jiang, Jeoung Eun Lee, Vicken Sepilian, Kwang Yul, Dong Ryul Lee, Yi Zhang   +10 more
openalex   +1 more source

Effect of exogenous transcription factors integration sites on safety and pluripotency of induced pluripotent stem cells [PDF]

, 2020
Shankai Yin, Wenzhao Li, Guoping Yang, Yan Cheng, Qi Yi, Shao‐Hua Fan, Qianli Ma, Fanyi Zeng   +7 more
openalex   +1 more source

A human induced pluripotent stem cell-based modular platform to challenge sensorineural hearing loss [PDF]

, 2021
Azel Zine, Yassine Messat, Bernd Fritzsch   +2 more
openalex   +1 more source

Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells

Nature Biomedical Engineering, 2018
The ability of extracellular vesicles (EVs) to regulate a broad range of cellular processes has recently been exploited for the treatment of diseases.
Bohao Liu, Benjamin W. Lee, Koki Nakanishi, Aranzazu Villasante, Rebecca L. Williamson, Jordan B. Metz, Jinho Kim, Mariko Kanai, Lynn Bi, K. Brown, G. Di Paolo, S. Homma, P. Sims, V. Topkara, G. Vunjak‐Novakovic   +14 more
semanticscholar   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Induced pluripotent stem cell–derived mesenchymal stem cells enhance acellular nerve allografts to promote peripheral nerve regeneration by facilitating angiogenesis

Neural Regeneration Research
Previous research has demonstrated the feasibility of repairing nerve defects through acellular allogeneic nerve grafting with bone marrow mesenchymal stem cells. However, adult tissue–derived mesenchymal stem cells encounter various obstacles, including
Fan-Qi Meng, Chao-Chao Li, Wen-Jing Xu, Jun-Hao Deng, Yan-Jun Guan, Tie-Yuan Zhang, Bo-Yao Yang, Jian Zhang, Xiang-Ling Li, Feng Han, Zhi-Qi Ren, Shuai Xu, Yan Liang, Wen Jiang, Jiang Peng, Yu Wang, Hai-Ying Liu   +16 more
doaj   +1 more source