Results 11 to 20 of about 5,412,420 (313)

Pluripotency of induced pluripotent stem cells [PDF]

open access: yesJournal of Animal Science and Biotechnology, 2012
Recent studies have demonstrated that differentiated somatic cells from various mammalian species can be reprogrammed into induced pluripotent stem (iPS) cells by the ectopic expression of four transcription factors that are highly expressed in embryonic stem (ES) cells.
Kang Lan, Gao Shaorong
openaire   +3 more sources

Retrotransposons in pluripotent stem cells [PDF]

open access: yesCell Regeneration, 2020
AbstractTransposable elements constitute about half of the mammalian genome, and can be divided into two classes: the class I (retrotransposons) and the class II (DNA transposons). A few hundred types of retrotransposons, which are dynamic and stage specific, have been annotated.
Jingwen Wang, Junjiu Huang, Guang Shi
openaire   +3 more sources

Chromatin structure of pluripotent stem cells and induced pluripotent stem cells [PDF]

open access: yesBriefings in Functional Genomics, 2011
Pluripotent embryonic stem (ES) cells are specialized cells with a dynamic chromatin structure, which is intimately connected with their pluripotency and physiology. In recent years somatic cells have been reprogrammed to a pluripotent state through over-expression of a defined set of transcription factors.
Paul, Delgado-Olguín   +1 more
openaire   +2 more sources

Induced pluripotent stem cells are induced pluripotent stem cell-like cells [PDF]

open access: yesThe Journal of Biomedical Research, 2015
Gold is rare and precious, while pyrite (FeS2) is abundant and cheap. Pyrite is nicknamed fool's gold, since pyrite looks like gold and it is even shinier and brighter than gold. It is very difficult to recognize the differences between a real natural gold and a gold-like rock (pyrite) to non-professional persons[1], but we know that all that glitters ...
Song, Liting, Goldman, Emanuel
openaire   +2 more sources

GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]

open access: yes, 2013
Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Polgár, Zsuzsanna   +5 more
core   +1 more source

Generation and characterization of erythroid cells from human embryonic stem cells and induced pluripotent stem cells : an overview [PDF]

open access: yes, 2011
Because of the imbalance in the supply and demand of red blood cells (RBCs), especially for alloimmunized patients or patients with rare blood phenotypes, extensive research has been done to generate therapeutic quantities of mature RBCs from ...
Bönig, Halvard-Björn   +5 more
core   +1 more source

Pluripotency of Induced Pluripotent Stem Cells

open access: yesGenomics, Proteomics & Bioinformatics, 2013
Abstract Induced pluripotent stem (iPS) cells can be generated by forced expression of four pluripotency factors in somatic cells. This has received much attention in recent years since it may offer us a promising donor cell source for cell transplantation therapy. There has been great progress in iPS cell research in the past few years.
Chunjing Feng   +2 more
openaire   +3 more sources

miRNA in Pluripotent Stem Cells [PDF]

open access: yesRegenerative Medicine, 2010
Embryonic stem cells and induced pluripotent stem cells are characterized by their ability to self-renew and differentiate into any cell type. The molecular mechanism behind this process is a complex interplay between the transcriptional factors with epigenetic regulators and signaling pathways.
Uma, Lakshmipathy   +2 more
openaire   +2 more sources

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes [PDF]

open access: yes, 2014
Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to ...
Tang, D   +39 more
core   +1 more source

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

open access: yes, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G   +14 more
core   +1 more source

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