Results 21 to 30 of about 1,024,717 (349)

Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing

open access: yesNon-coding RNA Research, 2017
In recent years, different studies have revealed that adult mammalian cardiomyocytes have the capacity to self-renew under homeostatic conditions and after myocardial injury.
Elena Garreta   +3 more
doaj   +1 more source

Controlling the Bureaucracy of the Antipoverty Program [PDF]

open access: yes, 1966
Rapid progress made in various areas of regenerative medicine in recent years occurred both at the cellular level, with the Nobel prize-winning discovery of reprogramming (generation of induced pluripotent stem (iPS) cells) and also at the biomaterial ...
Abounit   +184 more
core   +4 more sources

Reconstructing aspects of human embryogenesis with pluripotent stem cells

open access: yesNature Communications, 2021
Understanding human development is of fundamental biological and clinical importance. Despite its significance, mechanisms behind human embryogenesis remain largely unknown.
B. Sozen   +5 more
semanticscholar   +1 more source

Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency [PDF]

open access: yes, 2017
Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells.
Adjaye, J   +15 more
core   +4 more sources

Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells

open access: yesStem Cells International, 2016
Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development.
Gergo Kovacs   +2 more
doaj   +1 more source

Regenerative strategies for kidney engineering [PDF]

open access: yes, 2016
The kidney is the most important organ for water homeostasis and waste excretion. It performs several important physiological functions for homeostasis: it filters the metabolic waste out of circulation, regulates body fluid balances, and acts as an ...
Garreta, Elena   +2 more
core   +1 more source

Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil [PDF]

open access: yes, 2018
Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in the context of several stem cell ...
Aljoufi, Arafat   +3 more
core   +1 more source

Activin-A and Bmp4 Levels Modulate Cell Type Specification during CHIR-Induced Cardiomyogenesis [PDF]

open access: yes, 2015
The use of human pluripotent cell progeny for cardiac disease modeling, drug testing and therapeutics requires the ability to efficiently induce pluripotent cells into the cardiomyogenic lineage.
Blinka, Steven   +8 more
core   +14 more sources

Fish Pluripotent Stem-Like Cell Line Induced by Small-Molecule Compounds From Caudal Fin and its Developmental Potentiality

open access: yesFrontiers in Cell and Developmental Biology, 2022
The technique of induced pluripotent stem cells has significant application value in breeding and preserving the genetic integrity of fish species. However, it is still unclear whether the chemically induced pluripotent stem cells can be induced from non-
Wenting Xu   +21 more
doaj   +1 more source

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]

open access: yes, 2017
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di   +13 more
core   +2 more sources

Home - About - Disclaimer - Privacy