Results 21 to 30 of about 173,671 (315)

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
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A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture [PDF]

, 2012
Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Lau, KX, Hughes, J., James N Hughes, Goh, HN, Joy Rathjen, Rathjen, J, Hwee Ngee Goh, Lau, K., Hughes James N., Peter D Rathjen, Rathjen Joy, Goh Hwee Ngee, Vassilieva Svetlana, Rathjen, P., Vassilieva, S., Hughes, JN, Goh, H., Familari, M., Kevin X Lau, Rathjen, J., Rathjen Peter D., Familari, M, Lau Kevin X., Mary Familari, Familari Mary, Svetlana Vassilieva, Rathjen, PD, Vassilieva, S   +27 more
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Fish Pluripotent Stem-Like Cell Line Induced by Small-Molecule Compounds From Caudal Fin and its Developmental Potentiality

Frontiers in Cell and Developmental Biology, 2022
The technique of induced pluripotent stem cells has significant application value in breeding and preserving the genetic integrity of fish species. However, it is still unclear whether the chemically induced pluripotent stem cells can be induced from non-
Wenting Xu, Wenting Xu, Huajin Li, Huajin Li, Liangyue Peng, Liangyue Peng, Liyu Pu, Liyu Pu, Sijia Xiang, Sijia Xiang, Yue Li, Yue Li, Leiting Tao, Leiting Tao, Wenbin Liu, Wenbin Liu, Jinhui Liu, Jinhui Liu, Yamei Xiao, Yamei Xiao, Shaojun Liu, Shaojun Liu   +21 more
doaj   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]

, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T., Biology of Reproductive Cells, Pirity, M., Rungarunlert, Sasitorn, Klincumhom, Nuttha, Rungarunlert, S., Dinnyés, András, Tharasanit, Theerawat, Dep Gezondheidszorg Landbouwhuisdieren, Klincumhom, N., Techakumphu, M., Pirity, Melinda, Dinnyes, A.   +12 more
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Pluripotent stem cell lines [PDF]

Genes & Development, 2008
The derivation of human embryonic stem cells 10 years ago ignited an explosion of public interest in stem cells, yet this achievement depended on prior decades of research on mouse embryonic carcinoma cells and embryonic stem cells. In turn, the recent derivation of mouse and human induced pluripotent stem cells depended on the prior studies on mouse ...
Junying, Yu, James A, Thomson
openaire   +2 more sources

Pluripotent Stem Cells and Their Dynamic Niche [PDF]

, 2016
Cell-seeded implants are a regenerative medicine strategy that aims to replace injured tissue and restore tissue function. Pluripotent stem cells are promising cell candidates for the development of regenerative medicine therapies as they have the ...
Reinwald, Y, El Haj, AJ, Bratt, J, Jessica Bratt, El Haj, A, Yvonne Reinwald, Alicia El Haj   +6 more
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Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Vassilieva, Svetlana G., Wobus, Anna M., Wolf, Eckhard, Prelle, Katja, Vassiliev, Ivan M.   +4 more
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Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies

Neural Regeneration Research, 2022
Non-human primates play a key role in the preclinical validation of pluripotent stem cell-based cell replacement therapies. Pluripotent stem cells used as advanced therapy medical products boost the possibility to regenerate tissues and organs affected ...
Ignacio Rodriguez-Polo, Rüdiger Behr
doaj   +1 more source

Signalling, cell cycle and pluripotency in embryonic stem cells [PDF]

, 2002
Pluripotent mouse embryonic stem (ES) cells can be expanded in large numbers in vitro owing to a process of symmetrical self-renewal. Self-renewal entails proliferation with a concomitant suppression of differentiation.
Burdon, Tom, Burdon, T., Smith, A., Savatier, Pierre, Smith, Austin   +4 more
core   +1 more source

The alternative 3′ splice site of GPNMB may promote neuronal survival after neonatal hypoxic–ischemic encephalopathy injury

Ibrain, 2022
This study aimed to decipher the effect of glycoprotein nonmetastatic melanoma protein B (GPNMB) on neonatal hypoxic–ischemic encephalopathy (NHIE) and its potential molecular mechanism.
Guo‐Jiao Chen, Shan‐Shan Yan, Jing‐Han Zhang, Ji Zhang, Isaac Bul Deng, Rong He   +5 more
doaj   +1 more source