A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug +2 more
wiley +1 more source
Abstract Applying the four‐dimensional variational (4DVar) method in nonlinear systems faces conflicts between a lack of long‐term dynamical information using a short assimilation window and a trap of local minima using a long window. Here, an adjusted analysis approach that incorporates a thought of pseudo‐orbit analysis adjusting into 4DVar was ...
Shujun Zhu +13 more
wiley +1 more source
Bacterial extracellular vesicles promote membrane repair and tolerance to polymyxin B. [PDF]
Bos J +5 more
europepmc +1 more source
Ceftibuten-polymyxin B combination alters resistance and cell wall gene expression in multidrug-resistant Klebsiella pneumoniae. [PDF]
Sturaro MC, Silva RCCD, Simionatto S.
europepmc +1 more source
An aryloxyphenol potentiates polymyxin against multidrug-resistant <i>Acinetobacter baumannii</i>. [PDF]
Lee K +9 more
europepmc +1 more source
Comparative study on the wound healing effects of local versus systemic application of Polymyxin B in mice infected with multidrug-resistant <i>Pseudomonas aeruginosa</i>. [PDF]
Ma C +6 more
europepmc +1 more source
RENAsym, a quantitative systems toxicology platform model, designed to predict drug-induced kidney injury indicates polymyxin B and valproate overdose toxicity potential while simultaneously demonstrating acetaminophen and valproate safety at therapeutic levels. [PDF]
Vallejo C +12 more
europepmc +1 more source
A comparative study of intravenous polymyxin B and colistimethate sodium on efficacy, safety, and cost comparison in treating pulmonary infections: a retrospective cohort study. [PDF]
Wang C, Guo X, Li L, Yang R.
europepmc +1 more source

