Results 101 to 110 of about 49,900 (290)

Evidence from mendelian randomization identifies several causal relationships between primary membranous nephropathy and gut microbiota

Renal Failure
Background Research has showcased a correlation between disruptions in gut microbiota and primary membranous nephropathy (pMN), giving rise to the concept of the ‘gut-kidney axis’.
Jianwei Wu, Jing Zhang, Gang Huang, Yinglian Zhong, Yi Yang, Peng Deng   +5 more
doaj   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

[111]-oriented PIN-PMN-PT crystals with ultrahigh dielectric permittivity and high frequency constant for high-frequency transducer applications

, 2016
The electromechanical properties of [111]-oriented tetragonal Pb(In1/2Nb1/2O3)-Pb(Mg1/3Nb2/3O3)-PbTiO3 (PIN-PMN-PT) crystals were investigated for potential high frequency ultrasonic transducers.
Shujun Zhang (19587298), Xuecang Geng (20230350), Zhuo Xu (1485511), Thomas R Shrout (20219376), Jun Luo (120285), Fei Li (143236)   +5 more
core  

Standardized porcine unilateral femoral nailing is associated with changes in PMN activation status, rather than aberrant systemic PMN prevalence [PDF]

, 2022
PURPOSE: Intramedullary nailing (IMN) of fractures is associated with increased rates of inflammatory complications. The pathological mechanism underlying this phenomenon is unclear.
TREAT-Research Collaboration
core  

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Matrix protein regulation of PMN oxidative metabolism during ischemia

, 1994
Matrix proteins upregulate polymorphonuclear neutrophil (PMN) oxidative metabolism in a normoxic environment. We sought to investigate the relationship between matrix proteins and adherent PMN oxidative metabolism during acute ischemia.
H. Simms, R. D'Amica
core   +1 more source

Bovine PMN responses to extracellular vesicles released by Besnoitia besnoiti tachyzoites and B. besnoiti-infected host cells

Frontiers in Immunology
Bovine besnoitiosis is a re-emerging cattle disease caused by the apicomplexan parasite Besnoitia besnoiti, which severely affects individual animal welfare and profitability in cattle industry. We recently showed that B.
Gabriel Espinosa, Constanza Salinas-Varas, Lisbeth Rojas-Barón, Christian Preußer, Elke Pogge von Strandmann, Ulrich Gärtner, Iván Conejeros, Carlos Hermosilla, Anja Taubert   +8 more
doaj   +1 more source

Boosting the Photoluminescence of Au@Cu12 Nanoclusters via Strategic Fluorine‐Atom Ligand‐Shell Engineering

Journal of the Chinese Chemical Society, EarlyView.
The photophysical performance of gold‐doped copper‐rich nanoclusters can be tuned by surface functionalization. Subtle ligand modification enhances intermolecular interactions, thereby reducing nonradiative decay and markedly improving photoluminescence. Comparative photographs and quantum yield values (Φ = 55% vs.
Navya Indla, Wei‐Jung Yen, Yu‐Rong Ni, Jian‐Hong Liao, Xiaoping Wang, Michael N. Pillay, C. W. Liu   +6 more
wiley   +1 more source

Direct fungal killing by PMN-DCs and protection by adoptive transfer of PMN-DCs.

, 2018
Canonical neutrophils or PMN-DCs were generated in vitro from the GMP cell line and co-cultured in vitro with fungi (A-D) or transferred IV into mice (E). (A) Fungal killing by canonical neutrophils or PMN-DCs during in vitro culture with C.
David B. Sykes (3188637), Michael K. Mansour (557907), John F. Kernien (3116514), Bruce S. Klein (150448), Zeina Dagher (5244344), Michael Gui (5244341), J. Scott Fites (4040438), Jeniel E. Nett (146237), Paige Negoro (5244347)   +8 more
core   +1 more source