Results 41 to 50 of about 49,900 (290)
Frontiers in ImmunologyIntroductionThyroid-associated ophthalmopathy (TAO) is considered to be an organ-specific autoimmune disease. Polymorphonuclear neutrophils (PMN) have been implicated in the pathogenesis of TAO.
Ke Jin, Qian Yao, Bin Sun
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Advanced Materials Technologies, EarlyView.This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
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Advanced Materials Technologies, EarlyView.ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable for point ...
Mohsen Hassani +9 more
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PMN-DCs associate with yeast and kill yeast at higher frequencies than canonical neutrophils.
, 2018 Mice were challenged with DsRed B. dermatitidis, and lungs were harvested at 7 dpi. (A) Representative plots showing canonical neutrophils, PMN-DCs and moDCs indicating the cells of each population associated with yeast (% Uvitex+). Inset histograms show
David B. Sykes (3188637) +8 more
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Myeloid-Specific Pyruvate-Kinase-Type-M2-Deficient Mice Are Resistant to Acute Lung Injury
Biomedicines, 2022 Infiltration of polymorphonuclear neutrophils (PMNs) plays a central role in acute lung injury (ALI). The mechanisms governing PMN inflammatory responses, however, remain incompletely understood.
Xinlei Sun +7 more
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LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
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Plasma level and clinical significance of ADAMTS13 in patients with primary membrous nephropathy
Linchuang shenzangbing zazhi, 2022 ObjectivePatients with primary membrous nephropathy （PMN） have an elevated risk of venous thromboembolism （VTE）. The aim of this study was to detect plasma level of ADAMTS13 in PMN patients complicated and uncomplicated by VTE and examine their clinical ...
Zhu Guo-qiang +3 more
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Advanced Science, EarlyView.Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
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PMN can purloin zymosan from other PMN in decomplemented serum.
, 2013 A. A PMN approaches from below a PMN laden with 24 zymosan, B. +11 min, 36 sec, crawls about it to the left, and C. +27 min, 12 sec, removes 11 zymosan from it. D. +44 min, 4 sec. Both PMN remain motile.
Anne Chevance de Boisfleury (427326) +1 more
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CD63 relocalizes to PMN cell surface during STM infection in PMN-HIOs.
, 2022 Immunofluorescent image of PMN-HIO lumen during STM infection showing CD63 localized to cell periphery as a marker of PMN activation. Arrow points to an example of CD63 localized to the cell surface of an MPO-positive cell. (TIF)
David R. Hill (2330602) +13 more
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