Results 61 to 70 of about 49,900 (290)

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Differential inhibition of polymorphonuclear leukocyte recruitment in vivo by dextran sulphate and fucoidan

Mediators of Inflammation, 1996
The selectin-mediated rolling of leukocytes along the endothelial cells is a prerequisite step followed by firm adhesion and extravasation into the inflamed tissue. This initial contact can be suppressed by sulphated polysaccharides.
N. Van Osselaer, M. Rampart, A. G. Herman   +2 more
doaj   +1 more source

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

Advanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang, Hui Yang, Baoyuan Zhang, Yongsu Ma, Kuangen Zhang, Peng Wang, Jiapeng Yang, Zaiqi Wang, Rong Liu, Xiaodong Tian, Ning Zhang, Yinmo Yang   +11 more
wiley   +1 more source

Electric field control of magnetic properties in FeRh/PMN-PT heterostructures

, 2018
We investigated electric control of magnetic properties in FeRh/PMN-PT heterostructures. An electric field of 1 kV/cm applied on the PMN-PT substrate could increase the coercivity of FeRh film from 60 to 161 Oe at 360 K where the FeRh antiferromagnetic ...
Tian Shang, Baomin Wang, Huali Yang, Zhan, Qingfeng, Yang, Huali, Qingfeng Zhan, Liu, Yiwei, Xie, Yali, Shang, Tian, Wang, Baomin, Yali Xie, Yiwei Liu, Run-Wei Li, Li, Run-Wei   +13 more
core   +1 more source

Increased neutrophil apoptosis in chronically SIV-infected macaques

Retrovirology, 2009
Polymorphonuclear neutrophils (PMN) from chronically HIV-infected individuals have been reported to be more prone to die. However, although non-human primates models have been extensively used for improving our knowledge on T cell immunity, the impact of
Gougerot-Pocidalo Marie-Anne, Hurtrel Bruno, François Stéphanie, Monceaux Valérie, Elbim Carole, Estaquier Jérome   +5 more
doaj   +1 more source

Diagnostic Accuracy of Salivary Periodontal Biomarkers Is Reduced in Patients With Crohn's Disease. [PDF]

Clin Exp Dent Res
ABSTRACT Objectives Patients with Crohn's disease (CD) are at increased risk of developing periodontal disease and may benefit from salivary biomarker–based monitoring for early detection and management. Given the previously reported reduced specificity of the salivary aMMP‐8 test in CD, this study aimed to evaluate alternative salivary biomarkers for ...
Toivanen A, Nur, Räisänen I, Gürsoy M, Gürsoy UK, Sorsa T, Rautava J.   +6 more
europepmc   +2 more sources

Progress in Strain Engineering of 2D‐Integrated Heterostructures for Ultrasensitive Sensors

Advanced Science, EarlyView.
 . ABSTRACT Two‐dimensional (2D) integrated heterostructures have emerged as a cornerstone in the advancement of next‐generation sensor technologies. These heterostructures, which combine materials with different dimensionalities, have led to significant breakthroughs in sensing performance and device integration.
That Buu Ton, Tuan Sang Tran, Duc Khanh Tran, Van Thanh Dau, Dzung Viet Dao   +4 more
wiley   +1 more source

PMN protein production.

, 2015
Protein production kinetics of irradiated and non-irradiated PMN. A—Pb infected mice (non-irradiated and irradiated); B—Zymosan (Zy) inoculated mice (non-irradiated and irradiated); C—PMN recruited by Pb infection and co-cultivated with Pb; and D ...
Giulia M. A. C. Bani (692173), Ana Carolina S. C. Mendes (692172), Maísa R. P. L. Brigagão (692174), Liana M. Verinaud (692178), Michael R. Hamblin (82790), Felipe F. Sperandio (692179), Zoilo P. de Camargo (513545), Gérsika B. Santos (692175), Luiz Cosme C. Malaquias (692176), Eva Burger (692171), Jorge Kleber Chavasco (692177)   +10 more
core   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

A comparative dielectric relaxation study of PMN-PT and PMN-PZ ceramics using impedance spectroscopy

, 2005
AC-impedance spectroscopic studies in the temperature range of 30-400 degrees C are carried out on solid solutions of lead magnesium niobate (PMN) with lead titanate (PT) and lead zirconate (PZ), both of them in the 65/35 atomic ratio.
PANDIT, P, KULKARNI, AR, GUPTA, SM, WADHAWAN, VK, PATRO, P   +4 more
core   +1 more source