Results 31 to 40 of about 1,783 (155)

Emerging coexistence of three PMQR genes on a multiple resistance plasmid with a new surrounding genetic structure of qnrS2 in E. coli in China [PDF]

Antimicrobial Resistance & Infection Control, 2019
Abstract Background: Quinolones are commonly used for treatment of infections by bacteria of the Enterobacteriaceae family. However, the rising resistance to quinolones worldwide poses a major clinical and public health risk. This study aimed to characterise a novel multiple resistance plasmid carrying three plasmid-mediated quinolone ...
Ying Tao, Kaixin Zhou, Lianyan Xie, Yanping Xu, Lizhong Han, Yuxing Ni, Jieming Qu, Jingyong Sun   +7 more
openaire   +5 more sources

Genetic Diversity and New Sequence Types of Escherichia coli Coharboring β-Lactamases and PMQR Genes Isolated from Domestic Dogs in Central Panama

Genes, 2022
Background: β-lactamase-producing Escherichia coli are a widely distributed source of antimicrobial resistance for animals and humans. Little is known about the susceptibility profile and genetic characteristics of E. coli strains isolated from domestic dogs in Latin America. Methods: We report on a cross-sectional study that evaluated E.
Virginia Núñez-Samudio, Gumercindo Pimentel-Peralta, Alexis De La Cruz, Iván Landires   +3 more
openaire   +2 more sources

PMQR Determinants Expression in Gram-negative Uropathogens Clinically Isolated from Hospitalized Patients with Pyelonephritis in Kharkiv, Ukraine [PDF]

The Open Urology & Nephrology Journal, 2017
Background: Resistance to beta-lactams and fluoroquinolones has been increasing in the treatment of urinary tract infections (UTIs), worldwide. Recent studies in Europe and the United States have demonstrated that steady increase in the rate of uropathogen’s resistance to commonly prescribed antibiotics is ...
Olga Chub, Aleksandr V. Bilchenko, Igor Teslenko   +2 more
openaire   +1 more source

Distribution of fluoroquinolone resistance determinants in Carbapenem-resistant Klebsiella pneumoniae clinical isolates associated with bloodstream infections in China

BMC Microbiology, 2021
Background The rate of fluoroquinolone (FQ) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is high. The present study aimed to investigate the distribution of fluoroquinolone resistance determinants in clinical CRKP isolates ...
Qing Zhan, Yanlei Xu, Bingjie Wang, Jingyi Yu, Xiaofei Shen, Li Liu, Xingwei Cao, Yinjuan Guo, Fangyou Yu   +8 more
doaj   +1 more source

High Carriage Rate of the Multiple Resistant Plasmids Harboring Quinolone Resistance Genes in Enterobacter spp. Isolated from Healthy Individuals

Antibiotics, 2021
Antimicrobial-resistant bacteria causing intractable and even fatal infections are a major health concern. Resistant bacteria residing in the intestinal tract of healthy individuals present a silent threat because of frequent transmission via conjugation
Yongyan Long, Xin Lu, Xiansheng Ni, Jiaqi Liu, Mengyu Wang, Xu Li, Zhe Li, Haijian Zhou, Zhenpeng Li, Kui Wu, Wei Wang, Liya Yang, Jialiang Xu, Haiying Chen, Biao Kan   +14 more
doaj   +1 more source

A longitudinal epidemiology study of fluoroquinolone-nonsusceptible Klebsiella pneumoniae reveals an increasing prevalence of qnrB and qnrS in Taiwan

Journal of Infection and Public Health
Background: Our objective was to investigate the prevalence of plasmid-mediated quinolone resistance (PMQR) genes in fluoroquinolone-nonsusceptible Klebsiella pneumoniae (FQNSKP) in Taiwan, 1999–2022.
Pei-Yun Kuo, Wei-Hung Lin, Shu-Fei Tang, Ya-Yu Cheng, Carl Jay Ballena Bregente, Tran Thi Thuy Duong, Ming-Cheng Wang, Ching-Hao Teng, Yi-Hsien Hsieh, Pei-Fang Tsai, Ying-Chi Li, Cheng-Yen Kao   +11 more
doaj   +1 more source

Prevalence of Plasmid-Mediated Quinolone Resistance Genes in Escherichia coli Isolates From Colonic Biopsies of Iranian Patients With Inflammatory Bowel Diseases: A Cross-Sectional Study. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Emerging evidence suggests that ciprofloxacin and other quinolones can be effectively used as adjuncts to immunosuppressive therapy in managing inflammatory bowel disease (IBD). Clinical isolates of Enterobacterales frequently exhibit quinolone resistance.
Alipour S, Owrang M, Rajabnia M, Olfatifar M, Kazemian H, Houri H.   +5 more
europepmc   +2 more sources

Expression of plasmid-mediated resistance genes ESBLs and PMQR among uropathogens, isolated from non-dialysis CKD patients with pyelonephritis

KIDNEYS, 2022
Urinary tract infections (UTIs) are thought to be the most common group of bacterial infections, worldwide. It is estimated that the proportion of UTIs remains at a high level reaching 150 million episodes per year worldwide and accounting for $6 billion in health care expenditures.
O.І. Chub, S.V. Teslenko, O.V. Chub
openaire   +2 more sources

Prevalence of Plasmid-Mediated Quinolone Resistance Determinants and OqxAB Efflux Pumps among Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae Isolated from Patients with Nosocomial Urinary Tract Infection in Tehran, Iran

Scientifica, 2015
Objective. Plasmid-mediated quinolone resistance (PMQR) plays an important role in the development of clinical resistance to quinolone. The aim of this study was to investigate PMQR determinants among extended-spectrum β-lactamases- (ESBL-) producing ...
Mehdi Goudarzi, Mehdi Azad, Sima Sadat Seyedjavadi   +2 more
doaj   +1 more source

Characterisation of Extended β-Lactamases and Plasmid Mediated Quinolones Resistancein Escherichia Coli from Shelter Dogs

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2019
The aim of this study was to determine the prevalence of β-lactamase (TEM, SHV, OXA), extended-spectrum β-lactamase (ESBL) and genes encoding plasmid mediated resistance to quinolones (PMQR) in extended spectrum cephalosporin (ESC)-resistant Escherichia ...
Andreea Paula COZMA, Elena Iuliana MĂCIUCĂ, Cătălin CARP-CĂRARE, Mihai CARP-CĂRARE, Cristina RÎMBU, Adriana ANIȚĂ, Dragoș ANIȚĂ, Dorina TIMOFTE   +7 more
doaj   +1 more source