Fluoroquinolone Prophylaxis Against Febrile Neutropenia in Areas With High Fluoroquinolone Resistance—An Asian Perspective [PDF]
Journal of the Formosan Medical Association, 2010 Febrile neutropenia remains a major cause of morbidity and mortality in patients receiving chemotherapy. Major prophylactic strategies include granulocyte colony-stimulating factor and antibiotics, the most widely used of which are fluoroquinolones ...
Esther Shu-Ting Ng +3 more
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BJUI Compass, 2023 Background Fluoroquinolone resistance is an issue of concern amongst physicians worldwide. In urology, fluoroquinolones are often used in the treatment of acute pyelonephritis and prostatitis, as well as infections caused by multidrug‐resistant pathogens.
Daryl Thompson +3 more
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Overexpression of Salmonella enterica serovar Typhi recA gene confers fluoroquinolone resistance in Escherichia coli DH5α [PDF]
Brazilian Journal of Medical and Biological Research, 2015 A spontaneous fluoroquinolone-resistant mutant (STM1) was isolated from its parent Salmonella enterica serovar Typhi (S. Typhi) clinical isolate. Unlike its parent isolate, this mutant has selective resistance to fluoroquinolones without any change in ...
M.A.M. Yassien, M.A. Elfaky
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Nalidixic acid—a good marker of fluoroquinolone resistance mechanisms in Escherichia coli [PDF]
Microbiology SpectrumThe purpose of this study was to evaluate how ciprofloxacin, pefloxacin, and nalidixic acid disks perform in screening fluoroquinolone resistance mechanisms in 278 Escherichia coli isolates collected from a prospective clinical material.
Sofia Kalinen +8 more
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Impact of fluoroquinolone resistance on the cost-effectiveness of empiric treatment for multidrug- or rifampicin-resistant tuberculosis. [PDF]
PLOS Global Public HealthThe WHO recommends the bedaquiline, pretomanid, and linezolid (BPaL) regimen with the additional fluoroquinolone antibiotic moxifloxacin (BPaLM) for initial treatment of multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB).
Chaelin Kim +4 more
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Factors Influencing Fluoroquinolone Resistance
Emerging Infectious Diseases, 2003 To the Editor: Recently, Scheld summarized factors that he considered to have an influence on the efficacy of fluoroquinolones (1). In the review, ciprofloxacin was presented as the most active fluoroquinolone against Pseudomonas aeruginosa with MICs typically two- to eightfold lower than those for levofloxacin, moxifloxacin, or gatifloxacin.
Daniel F. Sahm +3 more
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Emerging Mechanisms of Fluoroquinolone Resistance [PDF]
Emerging Infectious Diseases, 2001 Broad use of fluoroquinolones has been followed by emergence of resistance, which has been due mainly to chromosomal mutations in genes encoding the subunits of the drugs' target enzymes, DNA gyrase and topoisomerase IV, and in genes that affect the ...
David C. Hooper
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Fluoroquinolone Resistance in Neisseria gonorrhoeae [PDF]
Emerging Infectious Diseases, 1997 Fluoroquinolones and broad-spectrum cephalosporins are the most effective antimicrobial agents for the treatment of gonorrhea. However, clinically significant resistance to fluoroquinolones has emerged in Neisseria gonorrhoeae.
Joan S. Knapp +3 more
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Intrinsic fluoroquinolone resistance in Orientia tsutsugamushi
International Journal of Antimicrobial Agents, 2010 Scrub typhus is a public health concern for a population of over a billion humans, with an estimated incidence of one million cases/year in endemic areas. Although doxycycline remains the standard therapy, fluoroquinolones have been used successfully in a few patients.
Didier Raoult +2 more
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Trend of multidrug and fluoroquinolone resistance in Mycobacterium tuberculosis isolates from 2010 to 2014 in Korea: a multicenter study [PDF]
The Korean Journal of Internal Medicine, 2019 Background/Aims This study was conducted to evaluate the recent prevalence and trend of anti-tuberculosis (TB) drug resistance with a focus on multidrug-resistance (MDR) and fluoroquinolone resistance in South Korea.
Hyeonseok Kim +7 more
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