Results 31 to 40 of about 55,766 (252)

Overcoming challenges in metagenomic AMR surveillance with nanopore sequencing: a case study on fluoroquinolone resistance. [PDF]

Front Microbiol
INTRODUCTION: Antimicrobial resistance is an alarming public health problem, and comprehensive surveillance across environments is required to reduce its impact.
Bloemen B, Gand M, Ringenier M, Bogaerts B, Vanneste K, Marchal K, Roosens NHC, Dewulf J, Boyen F, De Keersmaecker SCJ.   +9 more
europepmc   +2 more sources

Using machine learning to predict antibiotic resistance to support optimal empiric treatment of urinary tract infections

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Background: Antibiotic resistance is pervasive in the Veterans’ Affairs (VA) healthcare system, with rates of fluoroquinolone and trimethoprim–sulfamethoxazole (TMP/SMX) resistance approaching 30% in E. coli urinary isolates.
Ben Brintz, McKenna Nevers, Matthew Goetz, Kelly Echevarria, Karl Madaras-Kelly, Matthew Samore   +5 more
doaj   +1 more source

Trends in fluoroquinolone resistance in Campylobacter [PDF]

Microbial Genomics, 2018
Members of the genus Campylobacter remain a leading cause of bacterial gastroenteritis worldwide. Infection is usually self-limiting but in severe cases may require antibiotic treatment. In a recent statement by the World Health Organization (WHO) Campylobacter was named as one of the 12 bacteria that pose the greatest threat to human health because ...
Sproston, Emma L., Wimalarathna, Helen, Sheppard, Samuel K.   +2 more
openaire   +2 more sources

Initial resistance to companion drugs should not be considered an exclusion criterion for the shorter multidrug-resistant tuberculosis treatment regimen

International Journal of Infectious Diseases, 2020
Objectives: We investigated whether companion drug resistance was associated with adverse outcomes of the shorter multidrug-resistant tuberculosis (MDR-TB) treatment regimen in Bangladesh after adjustment for fluoroquinolone resistance.
Pauline Lempens, Tom Decroo, Kya J.M. Aung, Mohammad A. Hossain, Leen Rigouts, Conor J. Meehan, Armand Van Deun, Bouke C. de Jong   +7 more
doaj   +1 more source

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. coli and K. pneumoniae, A. baumannii and P. aeruginosa: A Global Ecological Analysis

Antibiotics, 2021
(1) Background: It is unclear what underpins the large global variations in the prevalence of fluoroquinolone resistance in Gram-negative bacteria. We tested the hypothesis that different intensities in the use of quinolones for food-animals play a role.
Chris Kenyon
doaj   +1 more source

Fluoroquinolone-resistant Escherichia coli, Indonesia [PDF]

, 2005
In a recent, population-based survey of 3,996 persons in Indonesia, fluoroquinolone (FQ)-resistant Escherichia coli was prevalent in the fecal flora of 6% of patients at hospital admission and 23% of patients at discharge, but not among healthy ...
Mertaniasih, Ni Made, Kershof, Irma, Kuntaman, Kuntaman, Sri Lestari, Endang, Kershof, Irma M., Juliëtte A. Severin, Lestari, ES, Hadi, Usman, Kuntaman, K, Severin, Juliëtte A., Endang Sri Lestari, James R. Johnson, Lestari, Endang Sri, Verbrugh, Henri A., van Belkum, Alex, Ni Made Mertaniasih, Marijam Purwanta, Henri A. Verbrugh, Johnson, James R., Belkum, Alex, Severin, Juliette, Purwanta, Marijam, Usman Hadi, Johnson, JR, Kuntaman Kuntaman, Purwanta, M, Hadi, U, Belkum, Alex van, Irma M. Kershof, Alex van Belkum, Mertaniasih, NM, Verbrugh, Henri   +31 more
core   +1 more source

Acquired fluoroquinolone resistance genes in corneal isolates of Pseudomonas aeruginosa [PDF]

, 2020
Fluoroquinolones are widely used as an empirical therapy for pseudomonal ocular infections. Based on increasing reports on acquired fluoroquinolone resistance genes in clinical isolates of Pseudomonas aeruginosa, we investigated 33 strains of P ...
Subedi, D ; https://orcid.org/, Khan, M ; https://orcid.org/, Summers, S, Rice, SA, Willcox, MDP ; https://orcid.org/, Stapleton, F ; https://orcid.org/   +5 more
core   +4 more sources

Induction of prophages by fluoroquinolones in Streptococcus pneumoniae: implications for emergence of resistance in genetically-related clones.

PLoS ONE, 2014
Antibiotic resistance in Streptococcus pneumoniae has increased worldwide by the spread of a few clones. Fluoroquinolone resistance occurs mainly by alteration of their intracellular targets, the type II DNA topoisomerases, which is acquired either by ...
Elena López, Arnau Domenech, María-José Ferrándiz, Maria João Frias, Carmen Ardanuy, Mario Ramirez, Ernesto García, Josefina Liñares, Adela G de la Campa   +8 more
doaj   +1 more source

Dissociated resistance among fluoroquinolones [PDF]

Antimicrobial Agents and Chemotherapy, 1994
A panel of 190 clinical isolates of staphylococci, enterococci, Streptococcus pneumoniae, members of the family Enterobacteriaceae, and nonfermentative gram-negative bacilli were examined by agar dilution tests for susceptibility to five quinolones and six nonquinolone agents. Members of the family Enterobacteriaceae and staphylococci were divided into
K S, Thomson, C C, Sanders
openaire   +2 more sources

Defining fluoroquinolone resistance-mediating mutations from non-resistance polymorphisms in Mycoplasma hominis Topoisomerases [PDF]

, 2021
Often dismissed as a commensal, Mycoplasma hominis is an increasingly prominent target of research due to its role in septic arthritis and organ transplant failure in immunosuppressed patients, particularly lung transplantation.
Spiller, Owen B., Rodríguez, Nadia M., Jones, Lucy C., Kirsty Sands, Sharratt, Martin, Martin Sharratt, Portal, Edward A. R., Ian Boostrom, Sands, Kirsty, Nadia M. Rodríguez, Boostrom, Ian, Lucy C. Jones, Brian A. Mondeja, Edward A. R. Portal, Owen B. Spiller, Mondeja, Brian A.   +15 more
core   +1 more source