Fluoroquinolone Prophylaxis Against Febrile Neutropenia in Areas With High Fluoroquinolone Resistance—An Asian Perspective [PDF]
Journal of the Formosan Medical Association, 2010 Febrile neutropenia remains a major cause of morbidity and mortality in patients receiving chemotherapy. Major prophylactic strategies include granulocyte colony-stimulating factor and antibiotics, the most widely used of which are fluoroquinolones ...
Esther Shu-Ting Ng +3 more
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Fluoroquinolone Resistance Mechanisms in an Escherichia coli Isolate, HUE1, Without Quinolone Resistance-Determining Region Mutations [PDF]
Frontiers in Microbiology, 2013 Fluoroquinolone resistance can cause major clinical problems. Here, we investigated fluoroquinolone resistance mechanisms in a clinical Escherichia coli isolate, HUE1, which had no mutations quinolone resistance-determining regions (QRDRs) of DNA gyrase ...
Toyotaka eSato +8 more
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Risk assessment and transmission of fluoroquinolone resistance in drug-resistant pulmonary tuberculosis: a retrospective genomic epidemiology study [PDF]
Scientific ReportsFluoroquinolone resistance is a major challenge in treating Multidrug-Resistant Tuberculosis globally. The GenoType MTBDRsl Ver 2.0, endorsed by the WHO, was used to characterize fluoroquinolone resistance. The fluoroquinolone resistance rates in the MDR-
Vijayalakshmi Jawaharlal Nehru +7 more
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Fluoroquinolone resistance in urinary tract infections: Epidemiology, mechanisms of action and management strategies [PDF]
BJUI CompassBackground Fluoroquinolone resistance is an issue of concern amongst physicians worldwide. In urology, fluoroquinolones are often used in the treatment of acute pyelonephritis and prostatitis, as well as infections caused by multidrug‐resistant pathogens.
Daryl Thompson +3 more
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Overexpression of Salmonella enterica serovar Typhi recA gene confers fluoroquinolone resistance in Escherichia coli DH5α [PDF]
Brazilian Journal of Medical and Biological Research, 2015 A spontaneous fluoroquinolone-resistant mutant (STM1) was isolated from its parent Salmonella enterica serovar Typhi (S. Typhi) clinical isolate. Unlike its parent isolate, this mutant has selective resistance to fluoroquinolones without any change in ...
M.A.M. Yassien, M.A. Elfaky
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Fluoroquinolone Resistance among Clonal Complex 1 Group B Streptococcus Strains [PDF]
Canadian Journal of Infectious Diseases and Medical Microbiology, 2016 Fluoroquinolone resistance in group B Streptococcus is increasingly being reported worldwide. Here, we correlated fluoroquinolone resistance with mutations in gyrA, gyrB, parC, and parE genes, identified by mining whole-genome sequencing (WGS) data of ...
Alefiya Neemuchwala +3 more
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Nalidixic acid—a good marker of fluoroquinolone resistance mechanisms in Escherichia coli [PDF]
Microbiology SpectrumThe purpose of this study was to evaluate how ciprofloxacin, pefloxacin, and nalidixic acid disks perform in screening fluoroquinolone resistance mechanisms in 278 Escherichia coli isolates collected from a prospective clinical material.
Sofia Kalinen +8 more
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Global Fluoroquinolone Resistance Epidemiology and Implictions for Clinical Use [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2012 This paper on the fluoroquinolone resistance epidemiology stratifies the data according to the different prescription patterns by either primary or tertiary caregivers and by indication.
Axel Dalhoff
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Impact of fluoroquinolone resistance on the cost-effectiveness of empiric treatment for multidrug- or rifampicin-resistant tuberculosis. [PDF]
PLOS Global Public HealthThe WHO recommends the bedaquiline, pretomanid, and linezolid (BPaL) regimen with the additional fluoroquinolone antibiotic moxifloxacin (BPaLM) for initial treatment of multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB).
Chaelin Kim +4 more
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Increasing Macrolide and Fluoroquinolone Resistance in Mycoplasma genitalium [PDF]
Emerging Infectious Diseases, 2017 Escalating resistance to azithromycin and moxifloxacin is being reported for Mycoplasma genitalium in the Asia-Pacific region. Analyzing 140 infections, we found pretreatment fluoroquinolone-resistance mutations in parC (13.6%) and gyrA (5%).
Gerald L. Murray +7 more
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