Results 21 to 30 of about 5,793,605 (328)

Fluoroquinolone Resistance Mechanisms in an Escherichia coli Isolate, HUE1, Without Quinolone Resistance-Determining Region Mutations [PDF]

Frontiers in Microbiology, 2013
Fluoroquinolone resistance can cause major clinical problems. Here, we investigated fluoroquinolone resistance mechanisms in a clinical Escherichia coli isolate, HUE1, which had no mutations quinolone resistance-determining regions (QRDRs) of DNA gyrase ...
Toyotaka eSato, Shin-ichi eYokota, Ikuo eUchida, Torahiko eOkubo, Masaru eUsui, Masahiro eKusumoto, Masato eAkiba, Nobuhiro eFujii, Yutaka eTamura   +8 more
doaj   +4 more sources

Prevalence of macrolide and fluoroquinolone resistance-mediating mutations in Mycoplasma genitalium in five cities in Russia and Estonia.

PLoS ONE, 2017
Background and objectiveResistance in the sexually transmitted bacterium Mycoplasma genitalium to all recommended therapeutic antimicrobials have rapidly emerged. However, to date, internationally reported resistance surveillance data for M.
Elena Shipitsyna, Tatiana Rumyantseva, Daniel Golparian, Guzel Khayrullina, Amaya C Lagos, Inna Edelstein, Kai Joers, Jörgen S Jensen, Alevtina Savicheva, Natalia Rudneva, Larisa Sukhanova, Roman Kozlov, Alexander Guschin, Magnus Unemo   +13 more
doaj   +2 more sources

Fluoroquinolone Resistance in Campylobacter Absent from Isolates, Australia

Emerging Infectious Diseases, 2003
Fluoroquinolone resistance was detected in 12 of 370 Australian human Campylobacter isolates; 10 of these were travel-associated, and for 2 isolates travel status was unknown. No resistance was found in isolates known to be locally acquired. In Australia,
Leanne Unicomb, John Ferguson, Thomas V Riley, Peter Collignon   +3 more
doaj   +2 more sources

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis. [PDF]

Adv Sci (Weinh)
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Fries F, Herrmann J, Dal Molin M, Wormser Y, Risch T, Gao Y, Prosser G, Gubellini F, Mechaly A, Wallach JB, Castro A, Banerjee A, Rasheed S, Horn A, Müsken M, Kurz M, Sonnenkalb L, Dreyer V, Niemann S, Andres S, Schnappinger D, Kazmaier U, Reiling N, Müller R, Rybniker J, Petrella S.   +25 more
europepmc   +2 more sources

Fluoroquinolone-resistant Escherichia coli, Indonesia [PDF]

, 2005
In a recent, population-based survey of 3,996 persons in Indonesia, fluoroquinolone (FQ)-resistant Escherichia coli was prevalent in the fecal flora of 6% of patients at hospital admission and 23% of patients at discharge, but not among healthy ...
Purwanta, Marijam, Mertaniasih, Ni Made, Kuntaman, Kuntaman, Kershof, Irma M., Johnson, James R., Hadi, Usman, Lestari, Endang Sri, Verbrugh, Henri A., Severin, Juliëtte A., Belkum, Alex van   +9 more
core   +2 more sources

Distribution of fluoroquinolone resistance determinants in Carbapenem-resistant Klebsiella pneumoniae clinical isolates associated with bloodstream infections in China

BMC Microbiology, 2021
The rate of fluoroquinolone (FQ) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is high. The present study aimed to investigate the distribution of fluoroquinolone resistance determinants in clinical CRKP isolates associated with ...
Qing Zhan, Yanlei Xu, Bingjie Wang, Jingyi Yu, Xiaofei Shen, Li Liu, Xingwei Cao, Yinjuan Guo, Fangyou Yu   +8 more
semanticscholar   +1 more source

Predicting fluoroquinolone resistance in Mycobacterium tuberculosis [PDF]

, 2023
Tuberculosis killed an estimated 1.5 million people in 2020 and the spread of drug-resistant strains is an increasing threat. Fluoroquinolones are among the safest and most effective drugs used to treat drug-resistant tuberculosis, but fluoroquinolone ...
Brankin, Alice E.
core   +1 more source

Fluoroquinolone resistance in bacterial isolates from ocular infections: Trend in antibiotic susceptibility patterns between 2005-2020

Indian Journal of Ophthalmology, 2022
Purpose: To assess the fluoroquinolone resistance pattern and trends among bacterial isolates from ocular infections over a 16-year period and explore alternative antibiotics in fluoroquinolone-resistant strains.
Samrat Chatterjee, Deepshikha Agrawal, Sharad N Gomase, Swapnil M Parchand, Anil B Gangwe, Mihir Mishra   +5 more
doaj   +1 more source

Discovery of a Novel Mutation in DNA Gyrase and Changes in the Fluoroquinolone Resistance of Helicobacter pylori over a 14-Year Period: A Single Center Study in Korea

Antibiotics, 2020
The efficacy of fluoroquinolone-based eradication therapy largely depends on the fluoroquinolone resistance of H. pylori. The aim of this study was to investigate the changes in the primary resistance rate of H.
Su Yeon Rhie, Jae Yong Park, Tae-Seop Shin, Jeong Wook Kim, Beom Jin Kim, Jae Gyu Kim   +5 more
doaj   +1 more source

Prevalence of Mycoplasma genitalium fluoroquinolone-resistance markers, and dual-class-resistance markers, in asymptomatic men who have sex with men

Journal of Medical Microbiology, 2021
Introduction Failure of fluoroquinolones, the principal treatment option for macrolide-resistant Mycoplasma genitalium infections, has recently emerged.
Teck-Phui Chua, Kaveesha Bodiyabadu, D. Machalek, S. Garland, C. Bradshaw, E. Plummer, J. Danielewski, L. Vodstrcil, Michelle L. Doyle, G. Murray   +9 more
semanticscholar   +1 more source