Results 161 to 170 of about 21,552 (215)

Germline MLH1 c.-42 C > T is a likely pathogenic variant predisposing to a reduced-penetrance/modified Lynch syndrome phenotype featuring MLH1-methylated cancers. [PDF]

Fam Cancer
Buchanan DD, Alvarez R, Mahmood K, Clendenning M, Georgeson P, Walker R, Como J, Preston SG, Joseland S, Mohammadsaeedi K, Aguirre F, Zhou L, Hazelett DJ, Jenkins MA, Rosty C, Winship IM, Macrae FA, Dwarte TM, Nixon D, Hitchins MP, Joo JE.   +20 more
europepmc   +1 more source

Tiam1 up-regulation by long non-coding RNA ABHD11-AS1 sponging of miR-182-5p causes β-catenin pathway activation to promote hexavalent chromium lung carcinogenesis. [PDF]

J Hazard Mater
Bi Z, Wang PS, Liu Z, Finkelberg ML, Li E, Carlson D, Shroyer KR, Yang C, Wang Z.   +8 more
europepmc   +1 more source

Lynch Syndrome in Focus: A Multidisciplinary Review of Cancer Risk, Clinical Management, and Special Populations. [PDF]

Cancers (Basel)
Eroglu S, Birsenogul I, Bowen AP, Doyle JF, Pupkin SE, Villar J, Tarney CM, Gandia E, Pastor DM, Estrada-Veras JI.   +9 more
europepmc   +1 more source

Mismatch repair deficiency and microsatellite instability in adrenocortical carcinoma. [PDF]

ESMO Open
Altieri B, Kircher S, Herterich S, Jahn A, Teleanu MV, Lippert J, Landwehr LS, Kimpel O, Reuter M, Remde H, Stenzinger A, Glimm H, Bargou RC, Fröhling S, Ronchi CL, Appenzeller S, Fassnacht M, Kroiss M.   +17 more
europepmc   +1 more source

Multigene Germline Panel Testing in Gastric Cancer Patients in a Portuguese Population. [PDF]

Cancer Med
Mourato B, Cordeiro B, Costa Pinto F, Pratas N, Fronteira I, Areia M, Dinis R.   +6 more
europepmc   +1 more source

Pathological diagnosis experience and literature review of four cases suspected Lynch-like syndrome. [PDF]

Front Oncol
Cheng B, Liu S, Ding S, Quan L, Liu J, Xu L, Zhao H, Guo J, Sun S.   +8 more
europepmc   +1 more source

Integrative proteomics reveals mitochondrial and immune signatures of MLH1 exon 13 deletion in Lynch syndrome-associated colorectal cancer. [PDF]

Front Mol Biosci
Chang C, Cao Y, Zhang B, Chen J, Chen L, Li W, Wang G.   +6 more
europepmc   +1 more source

A rare subtype of lynch syndrome familial with co-mutation of EpCAM c.344T>C, MSH2 c.2744A>G, PMS2 c.1408C>T and APC c.5465T>A, case report and literature review. [PDF]

Front Genet
Lu G, Pan T, Deng C, Wan X, Wang Z, Hu T, Cheng X, Dong J.   +7 more
europepmc   +1 more source

Concordance Analysis of Microsatellite Instability via NGS and Mismatch Repair Deficiency via IHC in Endometrial and Colorectal Cancer. [PDF]

Target Oncol
Nero C, Salvatore L, Duranti S, Anderson G, Mastrantoni L, Karimi M, Mantini G, Minucci A, Maneri G, Giacò L, Santoro A, Panfili A, Piermattei A, Marino I, Caira G, Calegari MA, Trovato G, Iacobelli V, Salutari V, Normanno N, Fanfani F, Scambia G, Tortora G.   +22 more
europepmc   +1 more source

Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency. [PDF]

NAR Cancer
Fishwick KM, Gomez Vieito D, Greco G, Collotta G, Gatti M, Kulik AA, Guérois R, Corbeski I, Phadte AS, Senoussi I, Cejka P, Pluciennik A, Porro A, Sartori AA.   +13 more
europepmc   +1 more source