Results 31 to 40 of about 32,635 (241)

Vaccines to Prevent Meningitis: Historical Perspectives and Future Directions

Microorganisms, 2021
Despite advances in the development and introduction of vaccines against the major bacterial causes of meningitis, the disease and its long-term after-effects remain a problem globally.
Mark R. Alderson, Jo Anne Welsch, Katie Regan, Lauren Newhouse, Niranjan Bhat, Anthony A. Marfin   +5 more
doaj   +1 more source

SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS

Journal of Experimental Medicine, 1930
1. Sera from individuals acutely ill with lobar pneumonia possess the capacity to precipitate in high titre a non-protein somatic fraction derived from pneumococci (Fraction C). Following crisis the reaction is no longer demonstrable. 2.
W. Tillett, T. Francis
semanticscholar   +1 more source

Variation of growth characteristics of pneumococcus with environmental conditions

BMC Microbiology, 2019
Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood.
A. Tóthpál, Katherine Desobry, Shreyas Joshi, A. Wyllie, D. Weinberger   +4 more
semanticscholar   +1 more source

Pneumococcus nasopharyngeal carriage in children attending an academic hospital in Pretoria, South Africa, after the introduction of pneumococcal vaccine

Southern African Journal of Infectious Diseases, 2019
Background: In 2009, pneumococcal conjugate vaccine was introduced in South Africa. However, there are concerns that this could lead to an increase in colonisation of non-vaccine serotypes (serotype replacement). Methods: In a cross-sectional study, 350
Charity Newton, Harry Maake, Caroline Maluleka, Siyazi Mda   +3 more
doaj   +1 more source

Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life

Frontiers in Immunology, 2021
BackgroundDevelopment of vaccines to prevent disease and death from Streptococcus pneumoniae, and nontypeable Haemophilus influenzae (NTHi), the main pathogens that cause otitis media, pneumonia, meningitis and sepsis, are a global priority.
Kelly M. Martinovich, Tasmina Rahman, Tasmina Rahman, Camilla de Gier, Camilla de Gier, Elke J. Seppanen, Tilda Orami, Caitlyn M. Granland, Jacinta Francis, Mition Yoannes, Karli J. Corscadden, Rebecca Ford, Peter Jacoby, Anita H. J. van den Biggelaar, Anita H. J. van den Biggelaar, Lauren O. Bakaletz, Allan W. Cripps, Deborah Lehmann, Deborah Lehmann, Peter C. Richmond, Peter C. Richmond, William S. Pomat, William S. Pomat, Lea-Ann S. Kirkham, Lea-Ann S. Kirkham, Ruth B. Thornton, Ruth B. Thornton   +26 more
doaj   +1 more source

Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens

PLoS Pathogens, 2017
Naturally acquired immunity against invasive pneumococcal disease (IPD) is thought to be dependent on anti-capsular antibody. However nasopharyngeal colonisation by Streptococcus pneumoniae also induces antibody to protein antigens that could be ...
R. Wilson, J. Cohen, Mark Reglinski, R. José, W. Chan, H. Marshall, C. D. de Vogel, S. Gordon, D. Goldblatt, F. Petersen, H. Baxendale, Jeremy S. Brown   +11 more
semanticscholar   +1 more source

Deoxyribonucleases of Pneumococcus

Journal of Biological Chemistry, 1967
Abstract Two enzymes with deoxyribonuclease activity were isolated from Pneumococcus. One of these, an endonuclease active on both native and denatured deoxyribonucleic acid, produced 5'-phosphate-terminated fragments which, even after extensive degradation, were larger than mononucleotides.
S, Lacks, B, Greenberg
openaire   +2 more sources

Interim results of an ecological experiment — Conjugate vaccination against the pneumococcus and serotype replacement

Human Vaccines & Immunotherapeutics, 2016
Streptococcus pneumoniae has more than 95 serotypes, each of which presumably can cause sepsis, meningitis, pneumonia, and acute otitis media. Pneumococcal conjugate vaccines (PCV) targeted against a limited number of serotypes have nonetheless revealed ...
William P. Hausdorff, W. Hanage
semanticscholar   +1 more source

Impact of pneumococcal conjugate vaccine on the carriage density of Streptococcus pneumoniae and Staphylococcus aureus in children living with HIV: a nested case–control study

Human Vaccines & Immunotherapeutics, 2020
Nasopharyngeal colonization density of Streptococcus pneumoniae (pneumococcus) is associated with disease severity and transmission. Little is known about the density of pneumococcal carriage in children with HIV (CLH).
Tila Khan, Ranjan Saurav Das, Bikas K. Arya, Amrita Chaudhary, Jyotirmoy Chatterjee, Sangeeta Das Bhattacharya   +5 more
doaj   +1 more source

Effects of experimental protein-containing pneumococcal preparations on maturation of murine dendritic cells

Инфекция и иммунитет, 2021
Dendritic cells as the most active and highly specialized antigen presenting cells, play a key role in initiating immune responses. Currently, generation of medications activating dendritic cells for development of anti-infective and anticancer vaccines ...
N. K. Akhmatova, I. M. Gruber, O. M. Kukina, E. N. Akhmatova, I. D. Makarenkova, V. A. Stolpnikova, E. O. Kalinichenko, I. A. Bisheva, S. A. Skhodova   +8 more
doaj   +1 more source