Results 41 to 50 of about 22,008 (204)

The Political Economy of Patent Buyouts

open access: yesThe RAND Journal of Economics, EarlyView.
ABSTRACT Incentivizing innovation through buyouts may alleviate the social costs associated with patent power, but the political economy and feasibility of this potentially important financing mechanism have been understudied. We study an international setting of countries with different innovation and financing capabilities, and where financing ...
Amal Ahmad   +2 more
wiley   +1 more source

Personalized Cancer Vaccines in the Clinical Trial Pipeline

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
This study analyzes the current landscape of personalized cancer vaccine clinical trials, highlighting trends in vaccine platforms, trial phases, and geographic distribution. Peptide and dendritic cell vaccines dominate early‐stage research, with promising immune responses observed in melanoma, glioblastoma, and urothelial cancer trials.
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

Burden of pneumococcal disease in children in Cuba before the introduction of a novel pneumococcal conjugate vaccine

open access: yesJournal of Global Health Reports, 2019
# Background The Cuban heptavalent conjugate pneumococcal vaccine will be introduced for children beginning in 2020. We estimated the burden of pneumococcal cases and deaths in children 1-59 months in 2015.
Nivaldo Linares-Pérez   +4 more
doaj   +1 more source

Green Stool Predominance in Babies and Subsequent Bowel Function at 1–2 Years of Age

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To study the relationship between bowel function after birth and at 1–2 years of age in the prospective HELMi cohort of term infants. Methods We focused on infants with predominantly green stools (n = 152) for three consecutive weeks in early life and their sex, age, and delivery mode‐matched controls (n = 300), and evaluated bowel ...
L. Typpö   +5 more
wiley   +1 more source

Pneumolysin: Pathogenesis and Therapeutic Target

open access: yesFrontiers in Microbiology, 2020
Streptococcus pneumoniae is an opportunistic pathogen responsible for widespread illness and is a major global health issue for children, the elderly, and the immunocompromised population.
Andrew T. Nishimoto   +2 more
doaj   +1 more source

Trends in Hospitalisations Due to Respiratory Syncytial Virus in Swedish Children: A Nationwide Study 2010–2022

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Respiratory syncytial virus (RSV) infection is a leading cause of paediatric hospitalisations. This study describes annual RSV‐hospitalisation burden of disease, by gestational week of delivery, age and sex among children aged 0–17 years of age in Sweden, for the period 2010/11–2021/22.
Kristian Bolin   +4 more
wiley   +1 more source

Health economic considerations for pharmacogenomic services in the United Kingdom: The Centre for Excellence in Regulatory Science and Innovation in Pharmacogenomics

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Dyfrig A. Hughes   +4 more
wiley   +1 more source

Parental Socio‐Economic Factors and the Risk of Invasive Bacterial Infections in Children: A Register‐Based Finnish Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Little is known about how socio‐economic factors influence severe childhood bacterial infections. We explored whether parental socio‐economic status correlates with the risk of invasive bacterial infections in the offspring. Methods Data on children < 16 years with community‐acquired blood or cerebrospinal fluid culture–positive bacterial ...
Kyrönlahti Anniina   +6 more
wiley   +1 more source

STUDY OF PROTECTIVE ACTIVITY OF PROTEIN-CONTAINING ANTIGENS OF STREPTOCOCCUS PNEUMONIAE IN A HETEROLOGOUS SYSTEM

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Study protective activity of protein-containing antigens of pneumococcus, obtained from serotypes 6В, 10А, 14, 19F, 23F and 36R, against infection with heterologous strains of S. pneumoniae. Materials and methods. S.
D. S Vorobiev   +5 more
doaj  

CLINICAL AND BACTERIOLOGICAL PECULIARITIES OF THE ACUTE OTITES MEDIA IN CHILDREN OF 0–5 YEARS OF AGE: PROVISIONAL DATA

open access: yesПедиатрическая фармакология, 2012
Analysis of clinical peculiarities and etiological structure of otites in 150 children of 0–5 years of age hospitalized with the diagnosis «acute otitis media», which was proved otoscopically and at paracentesis, was conducted.
A. L. Perova   +4 more
doaj   +1 more source

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