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HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick+16 more
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Pneumocystis pneumonia in the twenty-first century: HIV-infected versus HIV-uninfected patients
Introduction: Pneumocystis pneumonia (PcP) has classically been described as a serious complication in patients infected with the human immunodeficiency virus (HIV).
C. Cillóniz+6 more
semanticscholar +1 more source
Risk factors for drug resistant tuberculosis in Leicestershire - poor adherence to treatment remains an important cause of resistance [PDF]
In the light of rising numbers of tuberculosis (TB) cases in the United Kingdom, the problem of anti-tubercular drug resistance remains a significant concern.
Hayward, AC+3 more
core +2 more sources
Pneumocystis organisms can cause pneumonia in mammals that lack a strong immune defense. The genus Pneumocystis contains many different organisms that can be distinguished by DNA sequence analysis. These different organisms are different species of yeast-like fungi that are most closely related to the ascomycete, Schizosaccharomyces pombe. Each species
openaire +2 more sources
BackgroundDespite modern intensive care with standardized strategies against acute respiratory distress syndrome (ARDS), Pneumocystis pneumonia (PcP) remains a life-threatening disease with a high mortality rate. Here, we analyzed a large mixed cohort of
Julius J Schmidt+10 more
semanticscholar +1 more source
Pneumocystis jirovecii is a fungal pathogen that can cause life-threatening infections in individuals who are immunocompromised. Acquired via inhalation, upon entering the respiratory tract, the fungi first encounter innate immune cells such as alveolar ...
Theodore J. Kottom+3 more
doaj +1 more source
Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children [PDF]
AW and JK are supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of AberdeenPeer reviewedPublisher ...
King, Jill+4 more
core +1 more source
The Pneumocystis life cycle [PDF]
First recognised as 'schizonts' of Trypanosoma cruzi, Pneumocystis organisms are now considered as part of an early-diverging lineage of Ascomycetes. As no robust long-term culture model is available, most data on the Pneumocystis cell cycle have stemmed from ultrastructural images of infected mammalian lungs.
Anna Martinez+7 more
openaire +5 more sources
The role of opportunistic pathogens as etiological agents of intrauterine infections
The study showed a high prevalence of markers of herpesvirus infections among mothers — from 71% to 98% of HSV, EBV and CMV infections and from 29% to 58% of HHV-6 infection.
V. V. Kosenchuk+8 more
doaj +1 more source
Pneumocystis is a fungal pathogen that can cause pneumonia in immunosuppressed hosts and subclinical infection in immunocompetent hosts. Mucosal-associated invariant T (MAIT) cells are unconventional lymphocytes with a semi-invariant T-cell receptor that
Lisa R. Bishop+2 more
doaj +1 more source