Results 51 to 60 of about 74,652 (269)

Co-evolution of the parasitic fungi Pneumocystis and their Muridae rodent hosts in Southeast Asia [PDF]

, 2014
Pneumocystis species are opportunistic and airborne-transmitted fungi that infect the lungs of numerous mammalian species. These highly diversified fungi are characterized by strong host specificity, probably associated with co-speciation. In this study,
Bezé, François, Chabé, Magali, Latinne, Alice, Morand, Serge   +3 more
core  

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity [PDF]

, 2010
Primacenes, novel ferrocene-primaquine conjugates, were synthesized and screened for their antimalarial and anti-pneumocystis activity. Primacenes obtained by coupling primaquine amino acid derivatives to ferrocenoic acid were significantly active ...
Jiri Gut, Joana Matos, Margaret S Collins, Melanie T Cushion, Nuno Vale, Paula Gomes, Philip J Rosenthal, Rui Moreira   +7 more
core   +1 more source

What do Pneumocystis organisms tell us about the phylogeography of their hosts? The case of the woodmouse Apodemus sylvaticus in continental Europe and western Mediterranean islands.

PLoS ONE, 2015
Pneumocystis fungi represent a highly diversified biological group with numerous species, which display a strong host-specificity suggesting a long co-speciation process.
Christine Demanche, Manjula Deville, Johan Michaux, Véronique Barriel, Claire Pinçon, Cécile Marie Aliouat-Denis, Muriel Pottier, Christophe Noël, Eric Viscogliosi, El Moukhtar Aliouat, El Moukhtar Aliouat, Eduardo Dei-Cas, Serge Morand, Jacques Guillot   +13 more
doaj   +1 more source

Acute fibrinous and organizing pneumonia with myelodysplastic syndrome and pneumocystis jiroveci pneumonia: a case report [PDF]

, 2021
Minjie Lin, Yingwei Zhang, Yuying Qiu
openalex   +1 more source

Interferon‐gamma blocking as a promising treatment for severe liver dysfunction in secondary hemophagocytic lymphohistiocytosis after liver transplantation

JPGN Reports, EarlyView.
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome that can occur after solid organ transplantation but remains underrecognized in this setting. The diagnosis is often delayed due to overlapping clinical manifestations with infection, rejection, or malignancy, and management becomes particularly ...
Chen Chen, Tao Zhou, Jing Jin, Yi Luo, Lijing Shen, Qiang Xia, Yongbing Qian   +6 more
wiley   +1 more source

Metabolomic Profiling of Lungs from Mice Reveals the Variability of Metabolites in Pneumocystis Infection and the Metabolic Abnormalities in BAFF-R-Deficient Mice

Journal of Inflammation Research, 2023
Heng-Mo Rong,* Han-Yu-Jie Kang,* Zhao-Hui Tong Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, People’s Republic of China ...
Rong HM, Kang HYJ, Tong ZH
doaj  

An evolutionary perspective on zinc uptake by human fungal pathogens [PDF]

, 2015
DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (Grant Number 102549/Z/13/Z).Peer reviewedPublisher ...
Wilson, Duncan
core   +1 more source

Genetic Polymorphisms of Superoxide Dismutase Locus of Pneumocystis jirovecii in Spanish Population

Frontiers in Public Health, 2019
Objective:Pneumocystis pneumonia remains a major opportunistic infection in immunocompromised patients worldwide. Colonization with Pneumocystis jirovecii has recently gained attention as an important issue for understanding the complete cycle of human ...
Rubén Morilla, Rubén Morilla, Rubén Morilla, Amaia González-Magaña, Amaia González-Magaña, Vicente Friaza, Yaxsier de Armas, Francisco J. Medrano, Francisco J. Medrano, Enrique J. Calderón, Enrique J. Calderón, Carmen de la Horra, Carmen de la Horra   +12 more
doaj   +1 more source

Refractory flare-up of severe bronchial asthma controlled with mepolizumab due to Pneumocystis pneumonia: a case report

Allergy, Asthma & Clinical Immunology, 2022
Background Biologics dramatically improve symptoms of severe asthma; however, various exacerbating factors may induce flare-up. Pneumocystis spp. have not been reported as a cause of asthma exacerbation during biologic use, although patients with severe ...
Kazuya Takeda, Toshiyuki Sumi, Yuta Nagahisa, Keigo Matsuura, Motoki Sekikawa, Hiroki Watanabe, Yuichi Yamada, Hirofumi Chiba   +7 more
doaj   +1 more source